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polygenic risk scores

Is It Ethical To Hand-Pick Your Child’s Genes? - Dr Jonathan Anomaly

Chris Williamson

Dr. Jonathan Anomaly opens his discussion on genetic enhancement by addressing the historical stigma surrounding IQ tests, noting how they were misused in the 1920s and 30s to justify restrictive immigration policies and eugenics before being banned under Nazi rule after Hitler discovered Jews score …

What Embryo Selection Means for Humanity - Dr Jonathan Anomaly

Chris Williamson

Dr. Jonathan Anomaly argues that embryo selection represents a significant technological advancement for humanity, primarily functioning to reveal existing genetic variation rather than tinkering with the human genome via gene editing. While public skepticism persists due to concerns about eugenics …

The Good Ol’ Days Were Way Worse - Fin Taylor & Horatio Gould

Chris Williamson

Historians Fin Taylor and Horatio Gould, hosts of a comedy-history podcast, argue that while modern life offers significant advantages like better healthcare and longer lifespans, it lacks the unique "sweet spot" found in previous decades before social media dominated culture. They contend that nost …

Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133

Lex Fridman

Professor Manolis Kellis of MIT argues that understanding human disease has shifted from traditional animal model studies to a paradigm driven directly by massive datasets derived from natural genetic variation in humans. Historically, scientists used perturbations on single genes in mice or flies t …