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serotonin

Optimize & Control Your Brain Chemistry to Improve Health & Performance

Andrew Huberman

In this episode of The Huberman Lab Podcast, Dr. Andrew Huberman delves into the foundational biology required to optimize brain chemistry for mental health and performance. He argues that all protocols—whether breathing exercises, supplements, or drugs—leverage a core set of biological mechanisms c …

How to Control Your Sense of Pain & Pleasure | Huberman Lab Essentials

Andrew Huberman

In this episode of Huberman Lab Essentials, Professor Andrew Huberman explores pain and pleasure as two opposite ends of a continuum managed by our skin's vast sensory network and interpreted by the brain. The skin acts as the body's largest organ, housing neurons in dorsal root ganglia (DRGs) that …

Understanding & Conquering Depression | Huberman Lab Essentials

Andrew Huberman

Major depression impacts approximately 5% of the population and stands as the fourth leading cause of disability, characterized by profound grief, sadness, anhedonia (an inability to experience pleasure), and a specific cognitive distortion known as anti-self confabulation. Unlike standard memory de …