Video summary
The video discusses the critical importance of how hormones are metabolized and eliminated from the body, arguing that many people suffer because their systems are unable to properly process these substances. The speaker explains that while hormones are designed to enter the body, perform their function, and exit quickly, this cycle breaks down when elimination pathways are blocked. If hormones cannot be effectively removed, they accumulate and cause significant damage to various organs. This is particularly relevant for individuals using hormone replacement therapy or medications like thyroid hormone, where the speed of release and the body's ability to clear them determine whether the treatment is beneficial or harmful.
A central theme of the discussion is the necessity of "taking out the garbage" before introducing new hormones into the system. The speaker emphasizes that simply adding estrogen or other hormones without ensuring the body can metabolize and excrete them safely is dangerous, potentially leading to serious health issues like breast or endometrial cancer. Proper elimination relies heavily on specific metabolic pathways involving enzymes like CYP2B1 and the conjugation process facilitated by glutathione. Without adequate support for these processes, synthetic hormones with long half-lives can linger in the body for weeks, whereas natural hormones are cleared much faster, highlighting why lifestyle factors are just as important as the medication itself.
To support this natural elimination process, the speaker advocates for a foundation built on stress management, dietary control of insulin, and optimizing thyroid function before considering hormone therapy. Cruciferous vegetables play a vital role in this strategy because they provide compounds that help the liver eliminate fat-soluble hormones. While supplements like DIM or glutathione can assist in forcing conjugation when necessary, the speaker notes that a diet rich in these vegetables often renders additional supplementation unnecessary. The ultimate goal is to minimize medication reliance by fixing the root causes through diet and exercise, ensuring that whatever goes into the body has a clear path to exit safely.
The video concludes with a strong warning against relying solely on conventional doctors who may prescribe hormones without testing for proper metabolic ratios or addressing underlying lifestyle issues. The speaker asserts that patients must take responsibility for 70% of their health solution through their own actions, such as eating well and managing stress, while medical professionals can only provide the remaining 30%. If a patient does not commit to these foundational lifestyle changes, hormone therapy becomes ineffective and potentially toxic. Ultimately, the message is clear: hormones are tools that require a healthy, functioning body to work safely, and ignoring the metabolic cleanup required for their removal puts one's health at serious risk.
Read the full video transcript
years and years ago. I've been on a
hypothyroid and been on thyroid
medication for years and I just
intuitively found I love taking it at
bedtime. I did not know why and I have
no side effects. I sleep great.
>> [laughter]
>> So, you're one of those junkies.
>> Totally one of those junkies. I never I
mean, of course that makes sense with
the pathways, but I did not and it's a
very quick release T4
solution. So, it's actually even more
likely to cause palpitations for the
average person, but not for me.
>> [laughter]
>> But not for you. See, the thing is there
there a lot of a lot of doctors as a
clients of mine they do the same thing
too because they research they they they
researchers they they working 24/7 most
of time. They wake up at 3:00 in the
morning and they writing notes down
because they just had a dream of
something going on, right? And I I do
with those clientele I said, "Hey, what
you need is T3 at bedtime." I said,
"What?" I said, "Yeah, yeah, you need
some thyroid at bedtime because you had
you had you had too much too much
epinephrine norepinephrine kicking in
your body." And the things like that.
And so,
>> Amazing.
>> who use medication for this purposes and
of course the last 10% of solutions is
hormones.
Keep in mind the hormones is a
quick-acting, goes in, gets the job
done, and get out. If the if you cannot
get out of the system, the hormones are
actually causing damage to the body.
>> Yeah.
>> That's why sometimes continuous form of
hormones is actually not good for you.
Having hormone-free period, having
not to use patches or long-term pellets
and things like that. Having some breaks
here and there sometimes is good for
you.
Uh
And so, hormone therapy has been very
it's it's one of those things that you
can try and it's not going to kill you.
So, you can try different different
avenues see what works for each and
every individual. But here's the thing.
Hormones also needs to be conjugated
which is a CYP2B1 is the enzyme pathway
that needs to conjugate these hormones
and get it off the liver out. And you
just pee it out. That's why you do urine
tests to to measure hormone levels
sometimes is because some of these
hormones have to be conjugated to get to
be released. The conjugation happens
from glutathione.
>> Yes. Yes.
>> So, all my patients on hormones are
glutathione as a combination. So, gets a
job in, gets a job done, glutathione
conjugates, gets rid of it, tomorrow's
the next dose.
>> Brilliant. Brilliant, brilliant,
brilliant. I just want to repeat for
those listening out there. You said we
need to start with the cortisol stress
hormone stress management, then we need
to go to diet and insulin management,
and then we need to make sure thyroid is
optimized before we go to that bottom
10% which is the hormones. And so many
women who don't know any better are
going to these little hormone pop-up
clinics on the corner and they're like,
"Give me estrogen." And they don't feel
well and they wonder why, right? So,
this is so critical. Now, the other
thing you said that I want to emphasize
for our listeners that I think is so
important is I talk about it as taking
out the garbage. Which means I'm giving
you estrogen. However, if you're not
taking out the garbage, we're in big
trouble. And the kinds of things like
breast cancer, endometrial cancer, those
are not risk if you're taking out the
garbage and we look at those
two-hydroxy, four-hydroxy, 16-hydroxy
ratios and they're healthy. So, I'm
always looking at how that person that
I'm putting on the hormone. So, the
average doctor maybe doesn't know any
better and only has, you know,
conventional estradiol or a patch at
their disposal and isn't really testing,
I think is doing a disservice because so
many women who either had breast cancer
like myself or who are worried about
those kinds of things, the worry is not
the hormone. It's the metabolism and the
genetics around that. Do you want to
comment a little cuz I think this is
such a piece that's missed right now as
people are just demanding hormones. I
feel like if they're not really looking
at the taking out the garbage, which is
the conjugation of glutathione, they
might be missing the boat.
>> So, you're absolutely correct, right?
Nobody's telling you this, which is
whatever needs to whatever goes into
your body has to come out.
If it does not come out, that stuff is
going to kill you, right? So, when we
take hormone therapy,
>> Right.
>> it the body has to metabolize these
hormones. Every hormone has a half-life.
All the natural hormones have about 12
hours half-life. The synthetic hormones
have 45 days half-life. That means it
stays in the body for at least 45 to 50
days. Whereas natural hormones or
bioidentical hormones only stays for 12
to 24 hours. But they still have to be
metabolized. And the metabolism happens
from from from different pathways. The
number one thing is always eating
cruciferous vegetables because they
donate those metal groups uh in in in
this diet to help eliminate those those
hormones, which are all fat soluble
hormones, through your liver out.
Alternatively, of course, we can use
glutathione to to force the conjugations
naturally. Now, in if you're not taking
a supplementation, I hate to use up my
glutathione reserves for conjugation. I
hate to do that part because there's so
many other things to do in life than to
just eliminate toxic chemicals outside
your body, too, right? But if you're
supplementing, then it's it's okay to
supplement a little bit more, so that
way you can activate both the pathways
as well. So, the conjugation happening,
it it needs to be simultaneously. And
over the years, I used to use a lot of
DIMs, which is diindolylmethanes,
indol-3-carbinols, I3C, sulforaphanes,
broccoli extracts. I used to use or
trimethylglycines. And I used to use I
used to use all these products in the
past whenever I give people estrogens
and testosterones. Today, guess what? My
needs have dramatically reduced because
I didn't give them glutathione. They
don't need any of these products. As
long as their diet is full of
cruciferous vegetables every single day,
I have no supplementation required. So,
my patients are feeling good because now
there's less medication. They take this
absolutely what's necessary. And they're
really fixing their diets and their
exercises plans.
>> And I love that you start there with the
stress and the diet because just like
you, we have I mean, we just have to
start with that piece because you can't
just go into this isolated thing and
take a substance without thinking about
how it impacts everything else. And the
stress in the food is hard. It's hard
work. If people would rather have a
pill, but it's so so critical to start
with those lifestyle changes.
>> Uh
Dr. Jill, you're absolutely wasting your
time
coming to me and you
>> Yeah.
>> if you're not doing your part.
>> Yes.
>> Right? Because I'm telling you 70% of
the solution you have it in your hands.
If you're not doing your part, I can
only do 30% at best, and this is if I'm
perfect. I'm not perfect. I'm telling
you right now.
>> Okay.
>> And so, if you don't come 70% my way as
my patient, I cannot help you.
>> Yeah.