The Real Long-Term Effects Of Marijuana & Alcohol - Dr Daniel Amen
Watch on YouTubeVideo summary
Dr. Daniel Amen identifies a critical disconnect between public perception and neurological reality regarding substances like alcohol, marijuana, and psilocybin, arguing that these are often mistakenly viewed as health foods or innocuous treatments for mental health issues. He points out that while Gen Z is shifting toward higher THC consumption compared to alcohol use—a significant pivot over the last 50 years—this trend comes with severe risks. According to Amen's extensive research involving imaging studies of thousands of users, regular marijuana use in teenagers and young adults correlates with decreased blood flow and activity across every area of the brain, effectively making their brains appear older than they are. Furthermore, specific regions responsible for learning and memory show significant underactivity, a condition he describes as failing to "love your brain." The discussion extends beyond cannabis to include alcohol, which Amen asserts also accelerates brain aging when visualized through scans. Drawing from his experience directing substance abuse treatment programs, he famously displayed posters of damaged brains alongside healthy ones in over 100,000 schools worldwide with the title "Which Brain Do You Want?" These visuals served as powerful motivators for patients and public figures alike; notably, musician Jonathan Cain of Journey saw his own brain scan after drinking two bottles of wine nightly, stopped immediately, and observed significant recovery within nine months. Amen emphasizes that damaging one's brain structure directly impairs decision-making, emotional regulation, social interaction, and overall functioning, creating a debt to future well-being paid by sacrificing present health. Amen attributes the unhappiness of current generations to a convergence of factors including misinformation about substances, toxic ultra-processed foods consuming 70% of young people's calories, negative news cycles designed for engagement rather than truth, and damaging social media comparisons that foster feelings of inadequacy. He critiques the irony where individuals use acute interventions like marijuana or psilocybin to treat symptoms such as anxiety or depression, only to find these substances predispose them to those very same issues in the long run if used recreationally. Instead of relying on external fixes that borrow health from tomorrow, he advocates for a lifestyle approach grounded in love and self-care, asking individuals daily whether their actions are beneficial or harmful to their neurological structure. Central to his philosophy is the concept of "brain envy," which Amen proposes as a more constructive motivator than Freud's notion of penis envy. He recounts seeing his own brain scan after playing football and suffering meningitis in youth, realizing it was less healthy than his mother's stunningly beautiful brain at age 93 despite her active life with many grandchildren. This realization sparked a desire to avoid having one's six-year-old self outperform them neurologically later in life. By fostering an appreciation for what constitutes a healthy brain and understanding the cumulative, lagging effects of poor habits versus good ones, individuals can make informed choices that protect their cognitive function over time rather than succumbing to slippery conscious experiences that mask underlying structural decline.
Read the full video transcript
Why do you think that this is the
unhappiest generation at the moment?
What's contributing to that? Because
they have brain problems. They think of
alcohol as a health food. They think of
marijuana as innocuous. They think of
psilocybin as the cool new thing that I
should do because it treats PTSD and
depression and I think I should do it at
the party I'm at Friday night. Uh I
think there are a series of lies that
are driving the problems we have. And
then if you take on top of that social
media where you think everyone else's
life is better than yours, the negative
news that is actually designed to hook
you to keep watching even though it
makes you angry um so that they can sell
you more copper underwear. and then take
70% of the calories the young people
consume are ultrarocessed.
Uh so we're poisoning their food. We're
putting toxic products on their bodies.
Um we're feeding them negative news,
negative comparisons on social media.
It's a shitow.
And the way out I believe is brain
health. Cuz when you ask yourself this
one question and this is really the one
question to unpack. Whatever I do today,
is this good for my brain or bad for it?
And if I can answer that question with
information and love, love of myself,
love of my family, love of the reason
God put me on earth, I just get better.
dig into the effect of alcohol,
marijuana, mushrooms on the brain. I
think we're seeing a huge downturn in
alcohol use and a huge uptick in THC use
at the moment. In fact, Gen Z are more
likely to smoke weed than they are to
drink alcohol. And that's, you know, in
the space of 50 years, a big pivot. Uh
so I'm interested to know what even
short-term and then slightly more
protracted you know social normal normal
use whatever normal recreational use of
alcohol weed and mushroom see the
disaster we have with our mental health
teenagers who use marijuana in their 20s
have an increased risk of anxiety
depression suicide and psychosis I'm not
a fan at all uh I published a study on a
thous0 in marijuana users. Until
recently, the largest imaging study
ever. Every area of the brain is lower
in blood flow and activity. Makes your
brain look older than you are. Um, now
I've known that for a long time. I'm
also a child psychiatrist and parents
would bring me their 16-year-old child
and they go, I think he has ADD. I heard
about your work with ADD or ADHD. I
think he has it. And I'm like, well, did
he have it when he was 10? Did he have
it when he was eight? Did he have it
when he was 12? No, no, no. I'm like,
we're going to do a drug screen. And he
came he had it when it started hanging
around with little Johnny from from two
doors down. That's exactly it. What's
happening functionally with THC that's
causing that effect in the brain? It's
decreasing activity and blood flow in
the brain. And then just recently
another group has nothing to do with me
published a study on a thousand
marijuana users, young marijuana users,
significant areas of their brain
involved with learning and memory were
underactive.
And it's like that's not loving your
brain.
And it's like but I can't deal with the
anxiety.
It's like, well, have you tried
diaphragmatic breathing or learning not
to believe every stupid thought you have
or theine? I'm like a huge fan of theine
from green tea of all things decreases
anxiety and helps you focus.
It's interesting that the
salve that some people are using acutely
to try and treat a symptom is
predisposing them to more of that
symptom once they come out the other
side of it. There's a poetic irony going
on there. Yeah. I wrote a book called
Feel Better Fast and Make It Last. And
it's like, I want you to do things that
help you feel good now and later as
opposed to now but not later. Yeah. You
don't want to be borrowing health and
well-being from tomorrow to pay it
today. No. What about alcohol?
It makes your brain look older than you
are. And when I first started scanning
people, I was the director of a
substance abuse treatment program. And
their brains look so bad, I actually put
them on a poster. And the poster hangs
in a 100,000 schools around the world
called which brand do you want? Alcohol,
marijuana, cocaine, methampetamine,
nicotine. Not good. None of them were
pretty or no. Um and it was I was like
so impressed. I was so impressed with
the visuals
um that actually for now I make my
patients posters. It's like here's a
healthy brain. Here's yours. Here's
yours if you get it healthy. And here's
yours if you don't five years from now.
And the title is Which Brain Do You
Want? Very motivating. Uh Jonathan Kaine
did my show. He's the guitarist. Uh
keyboardist for Journey, the band
Journey, and he wrote many of their
iconic songs.
um he saw his brain and he was drinking
like two bottles of wine a night and
stopped and that was 9 months ago and
hasn't drank since. I'm like so proud of
him. It's a real motivator for people
real if if you're smart and you realize
your brain, the physical functioning of
your brain is involved in everything you
do, how you think, how you feel, how you
act, how you get along with other
people. It's the organ of every decision
you make. If you're damaging it, you are
damaging your present and your future. I
think so much of it comes back to that
tension I spoke about earlier on that
our day-to-day conscious experience of
our own minds is the most salient thing.
And yet the structure that's
underpinning them is so opaque because
we don't get to know why am I feeling a
little bit worse this month versus last
month. Yeah, maybe, you know, I had to
send it a bit too hard at a few parties
and yeah, maybe I didn't get that much
sleep and yeah, maybe I've been eating a
lot of sugar, but like who's to say?
Sometimes I eat sugar and I feel fine
the next day. So, there's always the
it's very slippery, you know, not in the
same way I think that if you eat a
calorie surplus for a couple of months
and then you look in the mirror and you
go, I'm I'm a bit fluffy, you know, I
kind of I can see what's going on. Now,
if there was an external representation
of structurally what was happening to
our brains beyond our conscious
experience, which is so slippery, and
you can't draw those uh lines, um the
the the trend between what I did and the
impact that it had, and I'm going to
guess that a lot of this stuff's lagged
as well. It's not going to be
immediately, I smoke weed one day, my
brain immediately starts functioning
more differently. It's going to be
cumulative. It's going to build up over
time. It's going to be to do with acute
changes but turning into chronic like uh
state changes turning into trait changes
over time. So everybody can just no well
you know like I'll just it's another
well and nobody cares about their brain
because you can't see it right just like
you're saying you can see the wrinkles
in your skin or the fat around your
belly and you do something when you're
unhappy with it. And in 1991 when I
looked at my brain for the first time,
I'm a double board certified
psychiatrist by then. I was the top
neuroscience student in medical school.
Um,
I didn't care about my own brain.
But when I saw it and then I saw my
mom's brain, so I saw my mom's brain the
week before and her brain was stunningly
beautiful, which reflected her life. And
still 93, she's got 55 grandchildren,
great-grandchildren. She knows
everybody's name, everybody's birthday,
what's going on in everybody's life. I
was unbelievable how it reflected her
brain. And then I looked at mine and it
wasn't healthy because I played football
in high school. I had menitis when I was
a young soldier. I had bad habits. But
when I saw it, I'm like, "No, I'm not
going to have my six-year-old mother
having a better looking brain than
wiping the floor with me
neurologically." Yeah. So, I've came up
with this term called brain envy. I
always say Freud was wrong. Penis envy
is not the cause of anybody's problem.
I've not seen it once in 45 years. Brain
envy. You want to learn to You want to
want a better brain. And as I develop
brain envy, I'm like, "Okay, what do I
do to have a better brain?" This episode
is brought to you by Nomatic. Summer is
here and travel season is in full swing,
but let's be honest, your backpack was
probably built for a school field trip,
not international adventures, which is
where Nomatic comes in. I have been able
to travel the world with this bag right
here, because it's designed by people
who actually understand the chaos of
being on the move. Everything has its
place and no space goes unused. It's
compact enough to fit under the seat,
but somehow fits everything that you
need when you're on the go. And if
you're still on the fence, their product
will last you literally a lifetime with
a lifetime guarantee. So, this is the
final backpack that you'll ever need to
buy. And you can return or exchange any
product within 30 days for any reason.
So, you can buy a new bag, put your
possessions in it for a full month, and
if you don't like it, they'll just give
you your money back. And they ship
internationally. Right now, you can get
a 20% discount and see everything that I
use and recommend by going to the link
in the description below or heading to
nomadic.com/modernwisdism.
That's nomatic.com/modern
wisdom. Thank you very much for tuning
in. If you enjoyed that clip, the full
episode is available right here.
Go on, press it.