Israeli researchers discover Viagra may stop cancer from spreading | Innov'Nation
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Israeli researchers have achieved a groundbreaking discovery suggesting that an active ingredient found in Viagra could potentially stop cancer from spreading to other parts of the body. This finding bridges two distinct areas of scientific inquiry: experimental research using mouse models and human cell lines, which demonstrated that the drug restricts cancer migration, and epidemiological studies analyzing real-world data from Israeli health services. These analyses revealed a significant correlation between patients who used Viagra six months prior to their diagnosis and improved survival rates, hinting at what is known as "drug repurposing." However, experts emphasize that while these results are promising, they do not yet constitute definitive proof of prevention in humans without further clinical trials, particularly those investigating the potential synergistic effects when combining Viagra with statins.
The concept of drug repurposing involves re-evaluating existing medications for new therapeutic uses to accelerate treatment development and reduce costs. In this specific case, bioinformatics analysis identified a gene associated with cancer progression that is inhibited by Sildenafil, the active component in Viagra. The researchers argue that conducting rigorous clinical trials on current cancer survivors or patients could validate these findings and potentially offer a novel, accessible avenue for managing metastasis. This approach represents a significant shift from developing entirely new compounds to leveraging known drugs with established safety profiles but unexplored mechanisms of action against malignancy.
Beyond the medical breakthroughs, Israel's technological sector continues to showcase its innovation through various other startups featured in recent developments. One such company is Nanovail, which utilizes artificial intelligence and robotic arms to automate the harvesting of citrus fruits like oranges. By employing computer vision that mimics human sight, these robots can identify ripe fruit within dense foliage and harvest them with precision, offering a cost-effective solution compared to manual labor while ensuring high-quality results without damaging the produce. This technology addresses critical challenges in agriculture where skilled workers are scarce, providing farmers with reliable machinery capable of operating around the clock regardless of market competition for human labor.
Innovation is also reshaping urban infrastructure and consumer markets across Israel and globally. A startup called No Traffic has developed an autonomous platform that uses real-time data from cameras and radars to optimize traffic light signals, effectively reducing congestion by up to 50% in pilot cities without requiring major changes to existing road infrastructure. Simultaneously, the secondhand fashion market is being revolutionized by a social marketplace app that simplifies buying and selling pre-owned clothing through integrated logistics and community features. Meanwhile, an Israeli AI startup specializing in real-time video generation has reportedly entered advanced acquisition talks with tech giants like SpaceX for a potential deal worth up to $7 billion, highlighting the immense value placed on Israel's emerging artificial intelligence capabilities. Finally, China is attracting tourists not just for its culture but as a destination where technology itself is the attraction, featuring humanoid robots in hotels and factories alongside high-speed trains and drone light shows that showcase the country's rapid technological advancement.
Read the full video transcript
[music]
Hello and welcome to Inov Nation. I'm
your host Lin PL Meer and thank you for
joining. First, our headlines.
Now, it's a world's first. Israeli
scientists have discovered that an
active ingredient in Viagra may stop
cancer from spreading. We speak to one
of the researchers.
And from Israel to a meager sum of only
$7 billion, a three-year-old Israeli AI
startup could be heading for a massive
sale. and Elon Musk's SpaceX may want
in. And China, already a global
powerhouse in innovation, is now also
turning its technology industry into a
tourist hot spot. We will have the
details.
Now, we start with some groundbreaking
news here from Israeli soil because
scientists have discovered that an
active ingredient in Viagra may help
stop cancer from spreading. Siden Phil,
the drug better known by its brand name
Viagra, which as you know, of course, is
used to treat erectile dysfunction, but
it has also been investigated for a
range of other conditions because of the
way it affects blood flow. Now, in a
world's first, Israeli researchers have
discovered a completely different
potential use for the drug, namely
preventing cancer cells from spreading
to other parts of the body. So, for
more, it's my pleasure to introduce Dr.
Sama Hayek, not to be confused with the
famous actress Selma Hayek, of course, h
but equally uh important in stature. So,
thank you so much, Dr. Sama Hayek, for
joining me today. H you're one of the
leading researchers of this incredible
discovery. So let's start with the
headline. Viagra may stop uh cancer from
spreading. Is this actually what your
research has discovered?
First, thank you for having me. Second,
it's really important for me to explain
that this unique study has bridges two
scientific words. The first is the
experimental research using cancer cells
and mouse modeling which allowed our
court colleagues from vitamin institute
to investigate the biological mechanism
and test whether PDEA inhibition
restricts met metastasis. The second
part is the epidemiological research
study where we use real world data from
clarit health services in Israel which
is the largest HMO in Israel where we
allow which allowed us to examine with
the viatra was associated with better
survival among patients with cancer.
These two designs answer different but
complimentary question. Now for your
only question, our findings are really
very promising but the answer requires a
requires an important distinction. In
the experimental component, Viagra
restricted cancer cells migration and
metastasis across mouse and the human
cancer models. In the epidemiological
component which I led, we analyzed real
world clinical data and found
significantly better survival among
patients with cancer who had used Viagra
six months before the cancer diagnosis
and we found also that those response
relationship of the benefit of using
Viagra. Therefore, the experimental
results de demonstrate an antimastic
effect in research model while the human
data which is the epidemiological study
show a consistent survival ass
association. Together they provide
compelling evidence but the
observational finding don't yet prove
that Viagra prevent metastasis or
improve survival in patients. Thus we
need more clinical trial that that look
and investigate this association.
>> So how did you know where to look? Why
did you look specifically into Viagra?
>> So it's really important question what
you are bringing here because the whole
idea was originated from a
biioinformatics analysis conducted by
professor Ethan Robin and his research
group. They found computational method
to identify genes inhibit the that that
might inhibit the a cancer progression.
And one of the genes that they looked at
was the PDE5A
what really important and it it it's
it's it's it helps and it encodes the
enzyme inhibited by Viagra the which is
the active ingredient like inhibited the
side which is the active ingredient in
Viagra. So how do you then if if your
research is is really as promising as
you say and everything is being tested
how will this in influence cancer
treatment in the future?
>> So in that's the really important point
because we need more clinical trials to
look at the association of using Viagra
or Sidelinfel and statin. We need also
to mention that the combination between
Viagra and statin that's our our
analysis also showed had even more
beneficial effect. So for cancer
patients we need a new clinical trials
that include both of them and we should
then estimate the effectiveness of the
treatment and that's what it's called
drug repurposing. We need to do drug
repurposing for this for these two
medications to see if they the we in the
help of clinical trial to see the
effectiveness of both the drugs on
cancer survivors or on cancer patients.
>> Well, it's an amazing discovery
nonetheless and I can't wait to hear if
it really turns out the way we hope it
might. So, Dr. Samahayak, thank you so
much for your time today.
>> Thank you. Now, changing gears because
picking oranges may sound like one of
the simplest jobs in agriculture, but
for farmers, it's a billion dollar
problem problem. It's estimated that the
market for harvesting oranges and lemons
alone is worth around $1 billion a year
with a potential business opportunity of
some $10 billion over the next decade.
Now, an Israeli company is betting that
robots could do the picking using
artificial intelligence, computer
vision, and robotic arms to identify and
harvest fruit straight from the tree.
So, for more, I'm now joined by Isaac
Mazour, CEO and founder of Nanovail. Hi,
Isaac. Thank you for joining me.
>> Hi.
>> Um, it must be a nightmare for a robot
to pick these oranges because how do you
know that the robot how does the robot
know that the fruit is ripe, where it
is? How do you do it?
>> Well, first of all, he don't complain.
So, he does the job as he's been trained
and actually we teach him to do the job
and we help him to do the job by proper
design and he actually uh use several
technologies. One is the AI of course AI
which is his eyes and brain. He sees the
fruit and he sees the fruit the way
nature sees it. If even though the tree
is very dense and high in depth in
foliage, deep foliage, still light can
get in. So if light can get in, we can
see it as well. And we see the fruit, we
map the fruit, we map his environment
and we plan carefully how to approach
it, how to grip it and how to sep how to
trim it.
>> So how does it compare to a human
worker?
>> We don't really can compare one to one.
What we compare is the cost per per
kilogram, how much you pay eventually
for the picking. And we have about 30%
uh lower in price. But more important
than that, we are always ready to go.
Workers is not. Work case has a
competition. There's a you know is
shrinking and rise pricing is rising.
Robot will be always in in in ready for
your uh command. That's the big
advantage beside the cost. This is what
growers is looking for is ability to
plan and and to count on something which
is not subjected to fierce competition
every day.
>> And what about because you focus now on
citrus fruits like oranges. Um why
specifically those types of fruit and
like do you want or do you are you
preparing to venture out to other sorts
of fruits or vegetables?
>> The answer is yes. Simply the longer
answer is fruit oranges is what we call
the lowhanging fruit. It's large. It's
very visible and it's tough to pick for
a human being. It's okay for robot. So
this is where our contribution is is
entry point is the best. And of course
soon after we expand beyond sit beyond
citrus to uh any fruit that require
premium cutting cutting very carefully
and sensitive to any damage because if
you damage the fruit it's scrap you know
you scrap the result. So this stone
fruit, avocado, mango all are step by
step uh will get that.
>> And what about you just received a
European vote of confidence. Can you
tell us about this? This is a great
achievement for us actually considered
the odds you know one one over 50 and I
think it was a great appreciation to and
recognition of our technology
our value to the uh to the community our
value to the growers and our execution
capability is very experienced people
I'm seriously entrepreneur I've been
build I built capital equipment business
in semiconductor actually in very
different market but still the
experience is uh is is is valuable for
this to build an organization for
servicing a capital equipment across the
world.
>> Well, it's amazing that you got this
vote of confidence. So, a big
congratulations.
>> Thank you,
>> Isaac Bazour, CEO and founder of
Nanovail. Thank you for your time today.
Now, who hasn't cursed their way through
endless traffic jams in a big city? No
traffic may have found a solution for
municipalities around the world. The
startup is working to optimize traffic
flow and in turn reduce pollution. More
in this report.
>> During rush hour, cities grind [music]
to a halt. In most major cities, traffic
lights still operate without taking
realtime traffic conditions into
account. So, how can we optimize road
traffic? The solution may have been
found by [music] the startup No Traffic.
Founded in 2017, the company has
developed the first autonomous urban
traffic management platform [music]
powered by artificial intelligence. Its
goal to eliminate traffic jams and make
streets safer in real time.
>> [music]
>> We understood that traffic has gone
relatively through a very little change
in the past 100 years and there has been
some change but we thought that using
technology we can make a major [music]
breakthrough and that's what brought the
company with a number of high-tech folks
that didn't really know a lot about
traffic to turn us into the one one of
the leading traffic companies today. She
reaches a traffic light at 2 in the
morning. She's the only one there, but
she gets a red light. Why should she get
a red light? Okay, if there's nobody
there, she should get a green. Okay,
that's just one small example of how we
can improve.
>> The principle is simple but highly
effective. The company installs smart
devices on traffic lights equipped with
cameras, radars, and AI chips. Within
milliseconds, the system identifies
everything moving through the
intersection, [music]
cars, buses, cyclists and pedestrians
and instantly adapts to the flow of
traffic.
>> So what we do is we look at the traffic
in real time. Uh whereas today in most
uh cities the traffic is the traffic
flows are based on statistical timing
plans. We look at the traffic in real
time and make realtime decisions based
on what's act on the traffic flow that's
actually out there. Now what we also do
is we're running not just a system we're
actually running a platform. I'll give
you an example. In one of the big cities
in uh in the US,
uh a stadium, football stadium, Monday
Night Football, the the corridor that we
optimized, no police. Okay, it was just
uh just the optimization that just the
optimization work then and the traffic
was much better than it would have been
if uh if it would have been run by
police.
>> And municipalities don't even need to
modify their existing infrastructure.
Most cities already have some sort of
technology out there called a detection
technology. Okay. Then they moved
forward to video technology to radar
technology even thermal technologies
even LAR technologies now. So there are
different technologies and those are
already deployed. Now what we're doing
is we are utilizing
existing deployed in deployed technology
but we're taking down the old stuff and
putting up the new stuff.
>> Let's see it in action. What you got
here is a city. This is traffic before
we got there. And then you'll see up at
two weeks later, same day of same time
of day, same day of the week. Look at
the traffic. Okay. So, so what you see
here is that the whole queue just
disappeared. Okay. And by the way,
there's more cars running here than here
obviously. Okay. So, there's more
traffic running smoothly. [music]
Another thing you'll see here on this
side, look at the left turn. Okay.
because we actually see what's going on,
we will clear that left turn lane for
them so that they won't have those types
of issues. Right? So, this is part of
the optimization that I showed you
earlier.
>> And the results speak [music] for
themselves.
>> We've seen that uh in cities where we do
optimization, we've uh reduced traffic
congestion by 30 to 50% in in many
cases. [music] But one of the more
interesting things we've we've shown
that for every dollar spent on no
traffic technology, the city gets
economic benefit of somewhere between
$75 to $200. Okay, which is great for
the mayors because they see they're able
to calculate the reduction in
congestion. How much does that save the
citizens? Emissions obviously and
improvements in safety. So if there are
less accidents and less red light
running, then less people are getting
injured. The company is also firmly
focused on the future.
>> We see traffic evolving all the time.
Okay, there's more and more uh you see
all sorts of autonomous vehicles. They
can talk to each other. They do a very
good idea of talking to themselves to
each other, but somebody needs to die in
the sky. By the way, at every
intersection we deploy, we also have a
special antenna that's built for the
future. We are looking forward to, you
know, all the future stuff where cars
are going by themselves or anything like
that. Artificial intelligence hasn't
eliminated traffic just yet, but it may
have just put the brakes on it for good.
>> Israel's secondhand fashion market is
growing, but buying and selling
pre-owned clothes can still mean endless
messages, haggling, and araging meetups.
Now, Israeli startup Loop wants to make
resale as easy as ordering something new
with a dedicated marketplace for buying
and selling pre-owned fashion and the
payments and shipping built into the
process. So, for more, I'm now joined in
studio by Sasha Gasia. You are the
founder of Loop. Thank you for being
with me today.
>> Thank you, Lane, for the invitation.
>> Well, Sasha, please, we have 60 seconds
on the clock. Please, what is your
startup about? Okay, so looped um I I I
just f when I when I was in France, I
love to sell my clothes on on vintage
and honestly when I arrived to Israel,
uh I had a lot of clothes to sell and
there was no solution for that. Um so
the concept of loop is basically to sell
your uh clothes that you don't use
anymore. So loop is very easy. You take
a picture of your clothes. You put some
informations and it's in the app and
after someone will just buy it and you
have two options. You can just sell you
can just uh ship them into a locker. So
someone buy it in the app, you put it
into a locker and someone will get it at
home to the locker that is closest to
his home or you can just take in a
pickup like someone will come and take
it from you. So you don't have even to
move from your house. But it's not only
that in in loop we also have a social
part uh when you can just uh for example
add your avatar, add your photo uh
follow people, add friends. So, it's
really, I think, an app that you can uh
um both sell your clothes and enjoy uh
into adding people and have fun.
>> Well, how does it compare then to for
instance vintage? Because I think we all
know this platform, but you say you have
an edge over vintage.
>> Yeah. First of all, there is no vintage
in Israel. So, we take a place that
there was no one into it. So all the
concept of loop is not only to sell as I
said to sell clothes but it's also to uh
to add friends to follow people and for
example tomorrow when there will be
influencers that will be uh unlooped
which we begin to have now um you can
just follow them and buy their own uh
their own clothes that they don't use
and because you love your you love their
style um so that's the concept of loop
big difference is that really we have
this social that that vintage doesn't
have and as I said they are not in
Israel so we just uh We are just there
whether whether or not
>> and you think there's a big market for
it in Israel.
>> Yeah, huge one. Huge one. There is more
than 10,000 places in in Tel Aviv. 100
sorry 100 place in Tel Aiv that sell
secondhand like vintage shops. So there
is a big market for that. But most of
the time it's it's hard to find exactly
what you need because secondhand is very
special market. Um when you go to
secondhand shops you have to find
exactly what you like in the right size
in your right style and some most of the
time it's just like if there is one
clothes that you like uh you will not
find it in the right size for example.
So so that's something that uh that
looped solves because when you are
unlooped you can just browse and and
search for exactly the clothes that you
want and you have like thousands of
clothes when you are in a small market
in a small shop most of them you don't
have
>> and do you think do you have any
international aspirations if Israel
becomes too small? Yes, of course we are
already talking with some market. I will
not talk about them now. I think it's
it's a little bit early for that. But of
course, we have. But the thing is I
really think that Israel is already a
big market. Like we can see that time
for example in Israel is a billion
dollar company now. So there is a market
that is huge in Israel. There is big
opportunities. So there is no reason
that we will go already from now
outside. First I want to develop loops
inside of Israel instead of the country
and after we'll see if we have to go
international which I would love to.
Well, we will wish you the best of luck.
Sasha Garcia, the founder of Loop, thank
you for your time today.
>> Thank you very much.
>> Now, a nearly three-year-old Israeli AI
startup could be one of the ver could be
on the verge of a multibillion dollar
exit. And Elon Musk's SpaceX may be
among the companies fighting to buy it.
Deart, which specializes in real time AI
generated video, is reportedly nearing a
deal worth up to $7 billion. Natashi
Keruk reports.
>> Elon Musk is reportedly in talks to buy
an Israeli startup that is barely three
years old. Forget this, around $7
billion. And if this deal goes through,
it could be a pretty big moment for
Israel's AI industry. This company is
called Decart. And what it's building is
pretty wild. It develops AI models that
can generate video in real time. That
means that instead of an AI creating a
video and making you wait for it to
render, Decart's technology can create
and then respond to video almost
instantly as you interact with it. Its
tech can even generate entire
interactive worlds. And that is
apparently what caught Elon Musk's eye
because the billionaire has actually
been following Decart since 2024 when
the company launched Oasis, which is
basically a video game that's powered by
AI that generates the game world in real
time. Since then, Musk and Decart CEO,
whose name is Dean Lightersdorf, have
reportedly stayed in regular contact,
but Decart's bigger selling point isn't
actually gaming. The company says its
technology can generate AI video using
significantly less computing power than
competing models. And that is a huge
huge deal in the AI world because
generating video requires an enormous
amount of computing power. And surprise
surprise, computing power is expensive.
Now, Decart is in advanced talks to be
acquired by a major international
technology company. And here's where it
gets interesting. The company was
actually negotiating with Nvidia, but
just as those talks were nearing a deal,
another tech giant reportedly came in
with a bigger offer, and Decart's
founders decided to go with the new
bidder. So, who is it? Well, multiple
sources believe that Elon Musk's Space X
could be behind the offer. The crazy
part is that Decart was only founded in
September of 2023. It has around 100
employees and just three months ago it
raised $300 million at a $4 billion
valuation and now it could be sold for
nearly twice that. So for investors that
is obviously a massive massive return
and if SpaceX is the buyer well there's
another major implication for Israel.
SpaceX could establish its first R&D
center in Tel Aviv using Decart as its
base.
>> Natashi Kerick there. Now, China, of
course, is becoming more than a
destination for sightseeing. This
summer, tourists are flocking to the
country for a taste of the future with
robots, drone shows, AI, and high-speed
trains. Technology isn't just part of
the trip, it's becoming the destination.
Emily Frances has the story. China, it's
the new trend online, following earlier
viral travel trends like China travel
and China cool. As more international
visitors look to experience China beyond
the usual tourist hotspots and
technology is increasingly becoming part
of the itinerary. At a robotics
exhibition in Beijing, tourists can get
up close with humanoid robots watching
them make everything from coffee, flip
pancakes, dance, and even write Chinese
calligraphy.
>> I find it very fun. I think it's like an
amazing thing that uh China has
developed such incredible technology.
Um, we in Mexico don't have this many
robots. So, I think it changed my
perspective on how technology can
probably change the world in the future.
>> And some tourists are taking that
experience one step further, visiting
factories to see how the technology is
actually made. At Xiaomi's electric
vehicle factory in Beijing, hundreds of
robots carry out precision tasks along
the production line. They could see a
lot of interesting things that maybe
they wouldn't be able to see back home
in terms of the sophistication and
probably more than anything just the
scale. I think the scale and the level
of advancement would be pretty
staggering.
>> But the high-tech experience doesn't
stop at the factory floor. Tourists are
riding high-speed trains between cities,
using AI multilingual guides at scenic
locations, and watching massive drone
light shows in Shenzhen. convenient
stuff like these which make China very
cool and traveling in China very cool.
>> At the same time, visitors are looking
for more hands-on cultural experiences
from picking tea leaves in Kanan to
exploring China's historic cities and
shopping for its latest tech products.
And the numbers suggest the interest is
translating into real world travel with
China welcoming nearly 23 million
foreign visitors in the first half of
this year, up more than 20% from the
same period last year. Tourist spending
by international visitors has also
jumped with a reported 72.9%
year-on-year increase since June.
China's visa-free policies make getting
there easier. Travel agencies say
visitors are increasingly asking for
technology to be built directly into
their trips, including robot companies,
drone makers, autonomous driving
experiences, and even drone deliveries
at the Great Wall. It's a new kind of
tourism where the destination itself a
showcase for technology. China, what a
place. Now, is it a bird? Is it a plane?
Nope, it is neither. It is a robot that
can fly through the air and swim
underwater. Engineered by MIT, the robot
was inspired by diving birds like
petrols and puffins using its wings to
move through both air and water. It
costs just $300, can fly at over 13 mph
and swim at nearly 2.2 mph. The FAV
robot could fly autonomously along set
routts before diving underwater to
monitor wildlife or collect samples from
toxic algae blooms, volcanic lakes, or
even in areas near icebergs. And after
the initial breakthrough, the lab is now
seeking funding to develop the robot
even further.
And that's all we have time for today.
I'm your host, Lynn Plmeer. The show is
going on a twow week summer recess. So
I'll be happy to welcome you back in
September. Enjoy that last bit of summer
wherever you are. Thank you for watching
for now and I'll be seeing you very soon
here on I24 News.