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Dietary Treatment of Trigeminal Neuralgia Pain

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Trigeminal neuralgia is a debilitating condition characterized by brief, recurrent electric shock-like pains in the face, typically triggered by innocent stimuli such as light touch. While standard medical practice often relies on epilepsy medications like carbamazepine or surgical interventions when drugs fail, these approaches have significant limitations; many patients experience unsatisfactory pain relief or severe side effects, and surgery carries risks of complications, persistent pain, or new facial pain sensations in a substantial portion of cases. Consequently, there is a growing search for alternative treatments that can effectively manage this severe neuropathic pain without the drawbacks of invasive procedures or heavy medication reliance. A promising dietary approach involves adopting a low-saturated fat diet, inspired by Dr. Roy Swank's groundbreaking work on multiple sclerosis and further validated in studies involving trigeminal neuralgia patients. Research demonstrated that restricting saturated fat intake to approximately 10 grams per day led to dramatic improvements, with nearly all participants experiencing a significant drop in pain levels within just one month. This dietary intervention allowed many patients to reduce or stop their medications entirely and transformed excruciating pain scores from near the maximum down to minimal levels comparable to a minor paper cut, even for those who had undergone multiple failed surgeries or suffered from continuous atypical pain. Despite these striking results, such findings have largely been overlooked by the mainstream medical community due to a bias toward evidence-based medicine that prioritizes randomized controlled trials over observational studies and nutritional interventions. Critics often dismiss long-term dietary success stories because they lack randomization, ignoring the fact that healthy diets carry no downsides and can offer profound benefits, unlike expensive and risky pharmaceutical drugs. This skepticism is evident in how Dr. Swank's extensive research on multiple sclerosis was excluded from major reviews despite showing that patients could remain ambulant and disease-free for decades, suggesting that the medical field may be missing out on life-saving treatments simply because they do not fit rigid methodological criteria.
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[music] >> The trigeminal nerve comes off our brainstem and as its name suggests, splits into three main branches to innervate our face. The top branch goes to the forehead and eyes, the middle branch to the cheeks and upper lip, and the bottom branch to the chin, lower jaw, most of the tongue. Trigeminal neuralgia typically manifests as brief, recurrent electric shock-like pains in one of the branches on one side of the face and is typically triggered by innocuous stimuli like light touch to that area of the face. Attacks tend to only last a few seconds or a minute or two, but people can suffer dozens of attacks per day, which can be so severe they're highly disabling. Trigeminal neuralgia affects about 1 in 500 people with a higher prevalence in women with average age of onset in our 50s. An MRI of the brain is indicated to make sure nothing is compressing the nerve like a tumor, but there isn't anything actionable, then the standard medical approach is to try to control symptoms with epilepsy drugs like carbamazepine. Uh due to unsatisfactory pain relief and or medication side effects, as many as 50% of patients in specialty centers end up going into surgery. Though neurosurgical procedures can be highly effective, they may result in complications in as many as 29% with the pain staying the same or even worsening in 19% of the patients and the new and different facial pain felt after the operation in 33%. What else can be done? There are various ways scientists create lab animal models for neuropathic pain, including surgically tying off major nerves or damaging them with toxic chemicals, but another way is just feeding them a high-fat diet. Rats fed a diet high in saturated fat and cholesterol develop nerve damage, a significant narrowing of their nerve fibers and surrounding insulation. Found to be due to the diet-induced oxidative stress and inflammation. The researchers noted their study has some limitations. For example, the number of the rats in each group may be augmented. Uh the limitation I'm thinking of though is that they're rats. Then, at the 2012 annual meeting of the American Academy of Neurology, a study was presented low-saturated fat diet that is effective in trigeminal neuralgia, which was subsequently published the following year. It all started with a civil engineer and his friend. She had been suffering with severe trigeminal neuralgia for 21 years and was scheduled to go into surgery. He discovered Dr. Roy Swank's remarkable work on controlling the nerve disease multiple sclerosis with a diet low in animal fats and suggested she give it a try for her condition. She did and her pain dramatically improved, her surgery was canceled, and for 13 years and counting, she continues to feel better after decades of suffering before. So, our engineer teamed up with a neurologist to put it to the test to see if this was just a fluke. 55 patients with trigeminal neuralgia for an average of 8 years were placed on a diet with a goal of only 10 g of saturated fat per day, which is about 4% of calories. Nearly all of them had been suffering daily attacks of severe pain averaging 9.6 out of 10 on a scale [clears throat] of 0 to 10 despite medications and nearly a third had already gone through a total of dozens of failed surgeries. Uh the researchers even included a set of patients with atypical cases of trigeminal neuralgia with continuous, never-ending discomfort. Within 1 month, 96% of those with typical trigeminal neuralgia had their pain levels drop from nearly 10 out of 10 pain down to less than two out of 10. And that was after 72% were able to reduce or stop their medications altogether. They went from an average pain score of more than nine out of 10 down to an average pain of less than one within an average of 16 days after suffering for an average of eight years. Even the atypical continuous pain patients went from about a nine out of 10 pain level down to two out of 10 in a matter of weeks. The post-surgical patients after a total of dozens of failed surgeries and still suffering severe pain, same thing. They went from living with more than nine out of 10 excruciating pain down to less than one out of 10 which is like a little paper cut or something. Now, the post-surgical group took 20 days to get better instead of 16 days, but they'd been suffering for 11 years straight. Years of extreme suffering, then 20 days later, gone. They had the power all along at any time if they had known they could just change their diet. Every day that decade, instead of surgery after surgery, they were just 20 days away at any time from being free. By the time the study was sent for publication, the patients had been on the low saturated fat diet for an average of 20 months, and the only reported side effect was a weight loss of 5 to 75 lbs. The researchers recognized placebo effects could not be excluded, although dramatic and sustained improvement even in the post-surgical group with severe and intractable pain makes it unlikely. Uh they do acknowledge that the results seem too good to be true and call for further trials to be performed. Yet no such studies have been forthcoming. How is that possible? They reported some of the most striking findings in the entire field of pain medicine. Originally presented in the single most widely read and highly cited peer-reviewed neurology journal in the world, but it appears their study has been completely lost down the memory hole. The only reference to it that I could find in the entire medical literature was a single mention in a dental journal back in 2014. I'm reminded of the medical community's collective reaction to the multiple sclerosis work that inspired the trigeminal neuralgia study. Before we lost him in 2008 at the age of 99, Professor Emeritus of Neurology Roy Swank published the longest running study of diet and multiple sclerosis in history in one of the most prestigious medical journals in the world. His work has been considered the most effective treatment of multiple sclerosis ever reported in the peer-reviewed literature. In patients with early stage MS, 95% were without progression of their disease 34 years after adopting his low saturated fat dietary program. Even patients with initially advanced disease showed significant benefit. Today, no medication or invasive procedures ever come close to demonstrating such success. Dr. Swank concluded his study indicated that in all probability MS is caused largely by consumption of saturated animal fat. Again, when the gold standard systematic review dietary interventions for multiple sclerosis was published, it didn't even consider Swank's work because it did not fit the inclusion criteria. Uh Swank's study was excluded because it was not a randomized control trial as if you could effectively randomize people to stick to specific diets for 34 consecutive years. Demanding randomized trials makes sense for drugs, which are expensive and risky, killing large amounts of Americans every year, but a healthy diet has no downsides and even good side effects. So, we shouldn't have to wait on randomized controlled trials to start saving people's lives. This is a perfect example of how evidence-based medicine biases physicians against nutrition. Doctors are encouraged to ignore any information that doesn't come from double-blind randomized controlled trials. Unfortunately, this approach can easily degenerate into ignoring most of the truly important evidence. Like the dismissal of Dr. Esselstyn's work on reversing the progression of coronary artery disease with a plant-based diet, or Dr. Kempner's work at Duke, or Pritikin's work, or McDougall's work, or Dr. Barnard's work at the Physicians Committee for Responsible Medicine. Remarkably, a 50-year follow-up study was published on Swank's patients, who by then were in their 70s and 80s. The research concluded that with a healthy enough diet, those with multiple sclerosis can expect to survive and be ambulant and otherwise normal to an advanced stage. The accompanying editorial was dismissive, suggesting one should be cautious in drawing conclusions from the report. Not only was it not a randomized controlled trial, but a reasonable explanation was not provided to account for the positive results. The editorial ended with "The big question is, if the results are so stunningly impressive, why haven't other physicians, neurologists, and centers adopted this method of treatment?" That is a good question. Why, indeed.