Brain Surgeon: Dream Patterns, Liminal States, & Subconscious Exploration - Dr Rahul Jandial
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Dr. Rahul Jandial, a brain surgeon at City of Hope Cancer Center, challenges the conventional view of surgery and sleep by framing them not merely as mechanical procedures but as forms of art requiring finesse and talent rather than just intelligence. He explains that surgical instruments are often designed for specific handedness to ensure proper mechanics, much like cutting meat cross-grain to minimize damage; similarly, successful brain surgery involves delicate manipulation where tissue planes separate with minimal trauma when handled correctly. This concept extends to the nature of sleep itself, which Dr. Jandial argues is not a state of rest but an active period of intense neuronal activity known as "paradoxical sleep." During this time, the executive network in the prefrontal cortex—which handles logic and judgment—dampens while the imagination and emotional networks are liberated, allowing the brain to process information through dreams. He posits that dreaming is a vital evolutionary mechanism for threat rehearsal and maintaining creative complexity, ensuring neurons do not wither from disuse by simulating scenarios ranging from escaping woolly mammoths to navigating modern social situations. The discussion delves into "liminal states," or hybrid transition zones where cognition shifts between different modes of being, such as the delta zone between fresh and salt water in cenotes or the window period during sleep onset involving lucid dreaming and sleep paralysis. Dr. Jandial connects these natural liminal spaces to human experience, noting that phenomena like goblins on the chest are cultural interpretations of these transitional cognitive states. He emphasizes that while science can explain many aspects of dreams—such as how EEGs proved the brain remains electrically active during sleep—it cannot fully quantify subjective experiences like love or intuition. Consequently, he advocates for a balanced approach that respects scientific rigor without dismissing intuitive insights or "hunches," warning against both blind skepticism and manipulation by cultish rhetoric while encouraging individuals to tap into their emotional centers and creative capacities. Dr. Jandial further explores the dynamic balance between the brain's executive network (task-on) and imagination network (task-off), suggesting that creativity often flourishes in liminal moments like waking up, meditating, or engaging in flow states rather than through forced effort. He cites examples where injuries to the executive network, such as those seen in frontotemporal dementia or induced by alcohol, can liberate hidden artistic talents, illustrating how different brain networks compensate for one another. This interplay is crucial for mental health; excessive stress without coping mechanisms leads to "friendly fire" akin to autoimmune diseases caused by unregulated inflammation. He introduces the concept of a biological thermostat that must be modulated through lifestyle choices and mindfulness, noting that while cortisol from thrill-seeking activities like surgery or sports does not necessarily accelerate brain aging in all cases, chronic unmanaged stress can damage neural structures if it exceeds necessary limits for growth. Addressing modern challenges, Dr. Jandial reflects on how external stimuli influence the dreamscape, referencing historical anecdotes about color television affecting dream colors and current debates regarding pornography's impact on erotic dreaming content. He suggests that while diet and media consumption play a role in providing raw material for dreams, the brain metaphorically processes these inputs rather than literally replaying them, as evidenced by PTSD flashbacks not manifesting as literal combat scenes but through emotional resonance. The conversation also touches upon emerging technologies like transcranial magnetic stimulation (TMS) used to treat depression and OCD by pulsing magnets to dampen or heighten specific brain regions without incisions. Dr. Jandial expresses cautious optimism about these tools, distinguishing between rigorous medical applications at elite centers and unproven consumer devices available online, urging a critical evaluation of new therapies that promise quick fixes for complex neurological conditions. Ultimately, the dialogue concludes with profound insights gained from caring for terminal patients over two decades, revealing universal patterns in how humans face mortality through reconciliation, forgiveness, and prioritizing family time. Dr. Jandial argues against the notion of linear progress toward wellness or a final state of clarity, instead viewing life as cyclical like nature's seasons, where periods of dormancy are necessary for renewal. He teaches that capacity to handle crises is developed during calm times rather than in the midst of them, urging individuals to build psychological resolve and coping skills before facing inevitable hardships. Whether dealing with addiction urges through controlled breathing or preparing for worst-case scenarios via meditation, he emphasizes equipping oneself with a toolkit of time-sensitive maneuvers to navigate life's uncertainties without losing one's sense of self amidst chaos.
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You just taught me there are left-handed
surgical instruments. What's that mean?
Um, for left-handed surgeons, the the
way some of the graspers click, um, it's
released with a maneuver where your
thumb pushes something outward.
>> Mhm.
>> For left-handed surgeons, that can be
sort of clunky. So, they make
instruments where it's outward. For the
left-handed surgeon is actually uh
inward towards the midline, and for the
right-handed surgeon, it's this way. So
there are left and right uh handed
instruments for different surgeons.
Needle drivers really where you click
onto a needle and it clasps so you don't
have to keep pressure on it and then you
can do your maneuver. Stake knives also
have serrations that lean one way or the
other. I just learned that.
>> I didn't know about that at all.
>> I didn't I know. I was just looking at
it because I've I've got a buddy who's
left-handed and he's like pointing all
this left-handed stuff out in the world.
>> Don't use that one. It's going to cut
completely incorrectly. What I did learn
was um when you have a steak, I mean I I
have to imagine this is slapbang in the
middle of your area of expertise, but
you want to never cut with the grain of
the meat. You want to be cutting cross
grain. Yeah. So that that that takes me
to what's beautiful about surgery is
like it's it's not like Legos. It's not
like, you know, hammers and chisel. It
can be with, you know, orthopedic
surgeries and spine surgery.
When you have somebody who can lightly
with a uh with a tweezer, a pickup we
call it, lift something up and you see
some membranes that are holding two
planes together. All right, let's say
you have two planes of tissue and
they're held together with this fine web
of membranes. You lift it up and you
take a scissor upside down, you just
spread lightly and the membranes fall
apart and the tissue comes apart. You're
not really trying to tug and pull. If
you do that with finesse, when the
patient wakes up, they feel less injury,
they feel less pain, less anesthesia,
the operation goes better, less blood
time. So, everybody thinks surgery is
all the same steps. Do these 10,000
steps. No, it's sculpting. It's art.
There's a finesse to it. And at some
point, uh, when you see somebody's good
at something, it's it's like ballet.
It's like something's being released.
They're not like, "And now I will do
this step." And, uh, that's the part I
love about it is talent. It's more it's
more talent than smarts. I love watching
people in between doing the thing that
they're supposed to do. So, a good
example of this is uh drummers. If
you're ever watching a drummer play
live, he loses a stick or he snaps or
something like that and he'll just
immediately switch and he'll be playing
with one hand and he'll just reach over
and he'll grab another one or if a
guitarist's playing and bing, off goes a
pick like that. And you'll watch him
without even thinking about it. He'll do
something, grab a pick from there, roll
it between his fingers, and go back. And
it's that liinal space. It's I'm just so
comfortable with my working environment.
Yeah.
>> And uh that's really cool to see.
>> So that word that's an interesting word
for me, liinal, because um that's kind
of the thing I've been thinking about a
lot. It's not the easiest thing to
explain to people, but I think that um
in nature, let me let me give you an
example. What I call a liinal space. I
was uh I used to dive a lot. I gave it
up. I had a scary accident. I almost I
almost uh ran out of oxygen uh real deep
uh off of Asia Asian coast there a Palao
and um it's I was like I've got kids
I'll do this when I'm older. Now I'm
older and I'm like ah I'm I'm you know I
don't have the energy but the place that
I love diving the most was the cenotes
of Yucatan like where it's all flat.
Maybe the asteroid landed there and
killed all the dinosaurs and that kind
of thing but they have caverns and there
there are river underground rivers that
meet the salt water. So when you go from
fresh water to salt water in our body,
salt water is a massive thing that has
to do with cognition and balance and a
lot of fundamental things are controlled
just by the salt in our blood and brain.
And but when you when you're diving and
you're in fresh water and then it's
called a halocline and you're now fresh
water is meeting salt water. There's
like five yards it almost feels like 5
meters where it's blurry.
>> So the transition from one state to
another at chemical psychological it
doesn't happen in a millisecond. There's
a liinal state. And so when you take a
look at the brain in 24 hours, I see at
least four or five liinal states. When
you're falling asleep, it's not a
complete I am awake and now I'm asleep.
There's a little window there about 15
minutes. Lucid dreaming when you're
asleep asleep and I can verify it and
you have a little return of awareness.
To me, those hybrid liinal transition
states give us an insight. I mean, it's
hard, right? Because I'm I'm I'm a brain
surgeon. And this is people expect
everything for me to be proven. But I'm
finding a lot of uh insight and
understanding from these uh different
liinal states. And then you can bring in
narcolepsy in the middle where people
suddenly fall asleep.
>> They have interesting thoughts. Um when
you wake up a third of the world feels
you know sleep paralysis and have have
like these feelings of a goblins on
their chest enough to where the stories
are built around different cultures. So
to me, those transition hybrid states of
cognition, of feeling, of experience, I
think that that's where the that's where
my head is really at these days. This
might be getting you out over your skis
a little bit, but someone asked me this
question the other day and I thought it
was such a good a great question.
What is something that you intuitit or
act as if is true or might believe but
you cannot prove with evidence or
science? Is there anything that comes to
mind with that? Well, I mean uh for me
the first thing that crossed my mind was
love. It's this you know the term used
to be ineffable and so like beyond
explanation but you know it's true
beyond articulation but it really motiv
motivates you or touches you spiritual
experiences right epiphies a hunch like
these are repeated experiences that
people are reporting right and dreams
could fall into that a little bit but
there are repeated things that we are
writing about through history and time.
Aristotle is Aristotle wrote about lucid
dreaming. Now that sounds like well come
on lucid dreaming. Uh but it's rigorous.
So Aristotle wrote about it thousands of
years ago a return of awareness within a
dream which sounds like how could you
ever prove that and 20 30 years ago and
increasingly now lucid dreaming is being
proven rigorously in sleep labs. So that
I think that's one example. But what
when I hear that, what it tells me is
don't deny those insights.
Don't rely on them blindly. Don't be
manipulated by somebody uh trying to
dazzle you with those kind of things.
You know, cults,
>> sexy rhetoric.
>> Yeah. Cults um catch you in a vulnerable
moment. My patients are vulnerable. The
sexy rhetoric isn't just uh you know
that this will heal you, but I was you
know there were there were a lot of like
stem cell clinics that that were
affecting children's hospitals in San
Die Children's Hospital San Diego is
real close to Mexican border of Tijuana.
>> Uh you know we're we're in Austin so
you're familiar with that. And there
there were patients families who were
going there to get stem cell treatments
that were uh it wasn't that they were
proven. We knew they were sham. They
weren't hurting them, but they weren't
helping them. And sometimes those moms
and kids would choose that over therapy
that was moderately effective. So, I
think there has to be some there have to
be some safeguards to vulnerable people
being manipulated. Yet I'm fully ready
to em embrace intuition, hunch, those
kind of things like where my my dog has
a instinct and hunch that comes from our
lyic system that exists within us. Uh
sort of the emotional centers of the of
the brain, the deeper structures of the
brain that we shouldn't deny those and
creative people learn to tap into those.
So the the challenge for me is always
how to liberate our understanding, my
understanding without it getting too woo
woo and leading to fluff.
>> It's such a good point, man. It's such a
good point. I I really think about this
a lot. The what level of rigor and
skepticism should we have without
closing ourselves off to alternative
approaches to things? And I I would say
I lean on the rationalist materialist
kind of evidency side of stuff. I tend
to have a a real um anti-conspiratorial
uh leaning to me. But that's been to my
detriment a lot of the time because I
think my I've probably said no to stuff
that my gut would have convinced me of
saying yes to. like my brain has
overruled my intuition and I'm kind of
trying to allow that to be tapped into a
little bit more and trying to get that
to reverse. Well, and so that's
interesting. So,
um, liinal states, these hybrid states
that exist in nature, deltas, where salt
water meets fresh water, where a waking
brain goes to our dreaming brain, that's
a cognitive delta, if you will. That's a
theme that I'm working on in my mind.
The other thing I'm working on is is
what what we're discussing now is that
to look at to look at our capacities as
as a thermostat. It's a modulation.
Inflammation's bad, bad, bad. I say
that's not true. We need some
inflammation to fight off beastings and
other things. But how is that thermostat
set right for our lives? We fight off
infections. Uh but if the inflammation
is too strong, it's like friendly fire
can cause autoimmune disease. So rather
than saying inflammation is bad or good
that this product is anti-inflammatory.
No, I actually need inflammation
sometimes. I need stress sometimes. I
need these capacities that have kept my
our species going uh uh sometimes. But
when they're running rampid without the
necessary stimulus for them, then we
have to identify it and use our coping
strategies and maneuvers and the things
that the wellness industry is presenting
to bring them back into the ecological
validity, which is real world scenario.
Where should my thermostat be?
>> Mhm. You mentioned dreams. Then is Freud
totally obsolete? Did he get anything
right when it comes to dreams? He got
one thing right for sure. Um, and before
before him it wasn't really clear that
dreams were coming from the brain.
That's a cool story too because
um so he's about 110 years old but
before he was the one like look it's
your desires gone wild your dreams it's
it's just freaky time and dreams and
it's but it was coming from your brain
and it it was only at that time it
wasn't clear that this creature this
human being lying on the ground mostly
limp body is cool brain must be off cuz
they're not moving. So, h how could that
inactive flesh, how could that inactive
like the hibernating screen on your
laptop, right? Like how could that
conjure up all of that crazy wild
adventures, dream state, dream
experiences? So it was a guy named uh
Burger he was looking he was trying to
actually so like the the the old school
people who were trying to understand
things they were open to hunch and
instinct and not to say paranormal but
something that they liked exploring
things that couldn't necessarily
uh be fully articulated but that didn't
stop the exploration the search for the
meaning in it. He felt like there was
this potential for mental telepathy. And
in looking for that, he put stickers on
the surface of patients scalps. And at
that time, they were just learning that
like a wire to a sticker on on your
scalp didn't didn't mean you had you
couldn't just you could just send
electricity in, but you could also
record. And so, he's the first one that
came up with the EEG. That later turned
into the EKG. An EKG is the three main
nerves on the surface of the heart
giving you a squiggle we're all familiar
with. An EEG is 96 stickers recording
the electricity generated by 100 billion
neurons that are like microscopic
jellyfish, right? It's just a recording
of the electrical phenomenon going
inside. And when he when he recorded
that EEG
um he didn't he let it run and at night
surprisingly there was still electricity
and that sat for like 20 30 years. But
that was the first time people are like,
"Wait a second, the brain is still going
off when we sleep." So much so that at
certain parts of the day and certain
parts of when we're in our sleep
dreaming brain, the electric the
electrical activity is so strong that
they call it paradoxical sleep that
while you're asleep, just based on how
wild your electricity is, you can't
actually tell if you're asleep or awake.
It's that hot. So it's not a quiet time.
And so that's what Freud did was say
dreams come to the from the brain. And
now we've come to understand that the
brain is always on. It's on a 24-hour
roughly cycle. You go into a cave and
you get it that people go in the cave
and they're still on a 24-hour cycle,
right? Circadian rhythms like we're all
built on this rotating planet like Venus
fly traps open and close, tides open and
close. We're on a 24-hour cycle. But the
brain electrically, physiologically, the
amount of glucose usage when we sleep,
the brain is not resting. And now that
allows us to say, well, what is it
doing? The most vibrant thing that the
dreaming sleeping brain is doing is
conjuring up dreams.
>> Okay, why do we dream then?
>> Well, that's a massive question, you
know. I mean, um
I would say the answer should come from
the information we now have. Okay, so
it's not chilling out. It's burning hot.
And this one, I got to unpack it a
little bit. when I just said look the
waking brain and the dreaming brain are
equally vibrant electrically but they
must be different. So one of the main
things that happens when you go from the
waking brain to the dreaming brain state
is certain continents in our in our
brain not like a spot but a network
called executive network. Now they're
trying to call it action network but
this is a very specific part of the
brain of the prefrontal cortex and it
needs a little bit of explanation. is
called the dorsal lateral prefrontal
cortex. The frontal loes are like this.
It's kind of on the outside. It's the
executive network. It's the conductor
that coordinates it all. It's
responsible for calculation, processing,
quick judgment, not a lot of instinct
>> that and and it tamps down other regions
such as the imagination network and
those deeper limbic structures that are
our hunch or how our my my dog can tell
when I'm trying to say, "Hey, um, hey,
come here." You know, like trying to
give him a treat to trap him to put him
back in his pen because we're going out
for the night. that instinct comes not
from the dorsal lateral prefrontal
cortex or of the prefrontal uh cortex.
So, so when you go from the dreaming
brain uh back to the waking brain or
waking brain to the dreaming brain, that
region is dampened. It's never on or
off. It goes from being like 51% active
relative to the imagination network to
49. So the dreaming brain has a dampened
executive network and a liberated
imagination network and movement regions
and emotional networks. So when we see
the shifts and as the executive network
comes down it's compensated by the
imagination network. So you get that
equivalent electrical activity. So when
you think of it that way, dreams, why we
dream has to be explained with what is
going on with the dreaming brain. It's
hyper visual, it's hyper creative, it's
uh it goes into tremendous social
situations. And my big idea about it is
it it's not what others have said like
it's threat rehearsal. If you run from a
woolly mammoth in your in your dream,
you're better off if you ever encounter
one. Or it's a nocturnal therapist. We
work out our emotions at night. It
doesn't make it doesn't fit the
complexity. We have PTSD flashbacks. So
what I think is happening is certain
regions of the brain that are generally
tamped down for us to perform the task
of the day are allowed to be liberated
in the safe space of our temporary
paralysis of our dreams. Because in the
brain, if you don't use certain neurons
in certain capacities, they will wither.
If I patch a kid's eye for therapeutic
purposes, where it lands in the
occipital lobe will physically wither.
And so I think the what we dream to
maintain our emotional and creative
complexity as a systematic process where
the brain takes turns in a 24-hour cycle
being executive network dominant and
imagination network dominant. So all
those all those capacities are there for
us for the next environmental event
we're not prepared for. So, if you spent
your entire day as a caveman logging all
of the different fruits that you'd
gathered over the last week and making
sure that your cave is clean and working
out where you're going to go to catch
the next mammoth, all of that is very
executive. It's very top down. There's
creative in some ways but not
intuitively creative. But you have maybe
not given yourself. The urgent always
overtakes the important and the urgent
is very rarely going to be a creative
pursuit. Task on versus task off. Yes.
Task on is outward and that's the
executive network. Of course, it
requires a little imagination and
everything to navigate. That's why it's
never completely on or off. And then
task off is daydreaming.
Dreaming itself is the most task off
thing and the brain wants to run
rampant. I mean it's wild. If you look
at some of the electrical activity, the
glucose usage, it is not a quiet time.
And so we can't deny that a process that
makes us lie down
burns that much energy when energy is
hard to get
is and has lasted through generations
and generations is essential. So my
feeling is that any collection of
neurons while they're in a dolphin like
dolphins do one brain at a time, well
half brain at a time so they can keep
paying attention. They'll they're
they'll sleep one hemisphere at a time.
Wow.
>> Penguins do like they do micro naps.
They like 10.
>> Flamingos do something weird with sleep
as well, right?
>> Well, the all the creatures they have
different ways, but when you get a
collection of neurons, they got to
sleep. And what happens when you sleep
is not rest. It's a different type of
neuronal activity. M the your body might
be resting. Your heart might slow down a
little bit. The liver's cool, body's
cool, but the brain's on fire. And just
to just to put it out there as a
surgeon, when I've moved livers between
moms to kids, you you could take a piece
of liver from a mom and move it to a
kid. I've transplanted hearts in
training. We're not really reconnecting
the nerves. Again, the the the the
bodily tissue is a little bit
autonomous. Sleep is not really for the
body. I'm not saying that sleep isn't
good for you. I'm not saying sleep
shouldn't be a performance goal. I'm not
saying that. I'm saying when our bodies
sleep, it's our brain that builds the
sleep pressure. And when we sleep, what
does the brain do? That's the most
vibrant thing it does. It dreams. So, I
think dreaming is an essential feature
of preserving a healthy brain and
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>> Is
is there something interesting about the
fact that we're conscious of our dreams?
because
>> you could imagine a world in which um
the body shuts down, the brain shuts
down and you don't have any conscious
recollection of the fact that this thing
happened. It was kind of I guess what
you're suggesting is there are certain
capacities that the brain needs and may
need in future. They're maybe not quite
as common as some other pathways that we
use more frequently. And dreaming is one
way for us to ensure that those myelin
sheets are kept nice and and and
lubricated. They're moving quite
>> accessible when we need them. They don't
they don't wither. They don't atrophy.
However, the fact that we're conscious
of this, the fact that we can recall it,
that there is a a phenomenological
emotional experience of going through
this, is that bit adaptive in your your
opinion or is that some spandrel side
effect like a light bulb that gives off
heat as well as light? Uh what do you
think about the the fact that we
actually know that we have been through
this thing? because I could imagine a
world in which you could uh retain the
capacity without having the experience
of being through it.
>> Yeah, that's it's a massive question.
It's a fantastic question and my opinion
is to tell a few stories about how how
some of these things happen. So, um
back to liinal states, I I don't think
any process in the brain, waking brain,
dreaming brain is a is a rigid onoff
process. So my my feeling is when we
remember some dreams
um they're like solar flares that have
leaked into our memory uh and we wake up
wake up we're we're accidentally sort of
holding on to the residue of massive
dreaming activity. That's my my hunch.
Um and and the way to think about that
is um the concept of self and
autobiographical memory. So when people
talk about self, self-worth, self this
the concept of self is created by a type
of memory. There's procedural memory,
tying your shoelaces, semantic memory,
stuff our phones record, you know, dates
and stuff, episodic memory, like the
episodes of our life. And the what
happens is they're stitched together by
a capacity called autobiographical
memory. And the thought here is from
people who have certain types of
psychosis when they can't separate out
their dream and waking state. Certain
patients with schizophrenia it becomes
quite confusing for them. So I think the
dreaming process is richly active in all
of us. The degree of recall is different
between us and different in different
stages of our life. And so when we do
remember a dream in the morning or we
wake up and we remember a dream, go to
the bathroom and sometimes fall back
into the dream that these are just uh
sort of the the residues of a vibrant
dream state that is breaking into our
consciousness. I don't think that um
it's by design. I think it speaks to the
capacity that we're never fully dreaming
and never fully awake. And the best
example of that is not uh sleep entry
that Salvador Dolly Dolly talked about
or sleep exit. We talked about sleep
paralysis. But in the middle certain
drugs that we give our patients for
Alzheimer's will make them have more
lucid dreams. So the awareness of the
dream state can happen when you're
falling asleep when you're waking up and
you're holding on to some of the dreams.
Uh and there are habits you can do to
hold on to them more. But also in the
middle of a dream, people can train to
lucid dream. I know that sounds like
okay there's a neurosurgeon talking
about that but it's rigorous uh
galantamines and acetylcholine u
antagonist that we give uh to improve
certain functions in Alzheimer's
patients and they report a dose
dependent increase in lucid dreaming
>> so I think the dream state and the
consciousness they're like two dimmers
and they're overlapping a bit and so
when we remember something in the
morning rather than thinking that it's
by design I think it's sort of like an
opport opportunity to have an insight
into ourselves at a very emotional, very
visual, very sexual time.
>> Yeah. Why did dreams often end up being
so emotionally intense, do you think?
>> Well, because when you look at the areas
that are activated preferentially in the
dream state, it's the lyic system which
are the emotional centers. When you look
at the the dreaming brain, the regions
that are activated, if you will, it's
the visual centers. It's the imagination
network and then equally you're
dampening you're dampening uh the
executive network so these big jumps of
ideas and creativity and associations
are not um discarded by the executive
network as they would be during the day.
It allows for that. Let me give you one
specific example that I thought was
really fresh when when I was asked to
prepare this book was um when you look
at thousands and thousands of dream
reports, not yours or mine, but like
mine feel wild, yours must feel wild.
But you start to see that very few
people report doing math in their
dreams. I'm not saying like somebody's
going to call in or write in and say,
"Yeah, but it's not like nightmares,
100% reported." It's not like um erotic
dreams, sexual dreams over 90%, teeth
falling out, being chased, flying. These
are common dreams, right? Math is very
rarely reported. And what I like is
okay, if I take hundreds of years of
patterns of dream reports, basically
surveys or Aristotle's comment about uh
lucid dreams. Now with modern
neuroscience, we they make sense. If the
executive network is is dampened that
does calculation, it kind of makes sense
to me that very few reports of math
occur in dream reports. Like that fits.
Executive Network goes down. Reports of
math go down. Imagination Network is
liberated. People report creative and
wild dreams. So it ties together what
people are reporting for years. Why
teeth falling out, falling, flying, you
know, three dreams that I would guess
almost everybody listening to this has
had in
>> and before electricity and after
electricity from the from the you know
horse and carriage all the way to
electric car
>> and
>> it's not like we needed to wait for
airplanes to be there to think that I
could fall out of an airplane or for
buildings to be sufficiently high that
you would fall from a skyscraper.
>> Exactly. So that so if we're getting
mental health
um is tied into certain families
nightmare one type of dream nightmares
clusters in families. So nightmare
disorder can happen
>> terrible well
or you know it that's that's a that's a
complex word I mean you can have things
cluster I mean you know maybe those
people are living in difficult situation
I so it's hard but
>> uh there is a dream that clusters in
family just like certain mental health
conditions would
share the same dreams with people living
in wildly different cultural times
>> something's built in and that that again
speaks to I I think uh the new
understanding we're having in the last
20 30 years as we can have people be in
brain scanners and fall asleep.
>> Have you got any idea about what makes
for universal
nightmare? Is this just something? I got
a big I got a big theory about it. Um
and so
so you know this book was um
um this book was important for me. It
was I had written a few others. One was,
you know, and then Penguin UK in London
said they've always wanted a book that
looked at dreams and dreaming from a
certain perspective of somebody with a a
complicated life story, somebody who's
had the professor chops, but also could
tell a story. And I I I really took it,
you know, it was uh it was wonderful
actually. I it kind of liberated me.
Part of that process was me rolling
around Dodger Stadium in LA and going to
pubs in London and sort of throwing this
out because it had to be for everybody,
right? It can't it's not me. And the
question I would get asked the most like
if dream wait if dreams are good for us,
why do we have nightmares? It was just
sort of a you got and so that was
chapter two.
Um nightmares are it's a tough thing to
explain because it obviously like why
why you know if if why would we why
would we cook that up? And so the way I
think about it is
um
you have to look at the mind as
um something that needs cultivating in
children just like walking and talking.
And so just like we're not fully formed
and we have to be taught to walk and
challenged to walk and talk and engaged
at the same time in the mind there are
certain cognitive developments that are
happening. So in they're called
longitudinal studies. They they had
families allow their children to be
woken up for like 22 years and report
like what they're dreaming about
different times and like when they were
two or three like it's just like it's a
blanket. It's it's not very dynamic.
It's not uh not a lot of movement. And
then around four and five, six,
nightmares arrive for every child. It's
rare to find I did a lot of pediatric
nurse surgery still do. I have three
sons in their 20s. They have to be told
that nightmares always arrive in
children, healthy children, unhealthy
children. some of my patients who who
had you know brain injuries. It seems to
be a part of the mind's development
that's built in. It arrives for
everybody and then almost invariably
very few kids have nightmare disorder.
It doesn't linger into the next day and
ruin their day like it does for adults.
So it's sort of like a wave of thinking
that a species of dreams that arrives
and then around 11 or 12 you have erotic
dreams that arrive whether kids are
having sex or not or teenagers are
thinking about sex or not they arrive
and and the last one I see is sort of
the matur like adolescence the brain
looks the same but we change who we are
so I think there are three waves of sort
of the development of the mind and what
happens around that age of four five and
six is also the development of something
called the default mode network. Like
until then, children have a hard time
reading minds. They can't tell if
smiling uncle means well or means harm.
And that capacity arrives at the same
time as nightmares. And so my big
hypothesis, it'll be hard to prove, is
that nightmares create a sense of self
versus other uh by having these
harrowing difficult experiences. It sort
of creates um that the world around me
is separate from who I am. And this
engagement with monsters and different
things creates this default mode network
that allows us to start to see ourselves
as separate from the world around us and
to be a little bit more critical in
evaluating the threats and the people
and their intentions around us. That's
my big thesis. And that would make sense
adaptively because before age four,
five, six, kids are so unindependent
that the need to be able to distinguish
uh between I am here and that is
something else is kind of pointless
because you're not let out of the sight
of mom or dad. Yeah, you're you're in
the rap still. You're very close. You're
not being led. I mean, I think that's a
good point. The other point is that um
that it's just like every every every
kid has to be told it was only it's only
a dream. It's only a nightmare. And that
there's this just like we talked about
liinal states in the beginning like in
psychosis people can't separate out uh
you know awake versus dreaming. Um and
that stitch autobiographical memory. We
need to know these are awake thoughts
and these are dream thoughts and dream
thoughts should not disrupt your awake
thoughts that there are these things
that happen in your mind but they're not
actually the the daily steps that link
your life together right that in
children
um I don't know if before nightmares
they know the difference between uh
waking thoughts and dream thoughts like
maybe nightmares informed the child it
was only a dream so it's always been a
puzzle to me Until then, do they not
know that what they experienced in their
thoughts while sleeping was actually not
real? Could be discarded. I guess that
the creativity network in kids is so
much more alike even when they are
awake. You you watch in the space of an
afternoon a child's a firefighter and a
postman and an astronaut and a sports
star and a rock star and asleep and then
awake again and back to being a postman.
And yeah, I I dream of being a I
literally do dream of being able to have
that level of creative access again.
>> And I think so that nightmares are
serving something fundamental because
they arrive in all of us. It is the
universal dream. We can all talk about
what what it what they serve and the
purpose. And the last thing I would say
about that to be a nightmare, it has to
wake you up. It's not a bad dream like
you wake up the next day, oo that was a
rough night. Nightmares have to wake you
up, sear your memory to be considered a
nightmare. It's the It's the dream that
has to wake you up and be vividly
remembered. So, I think there's some
mental cultivation going on with this
process that we all share. We'll get
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Do you think it's important to remember
our dreams? Have they got deeper wisdom
to tell us or should we just allow them
to be a sandbox that sort of lives on
its own? I I
think based on what I've learned, I I
think I think it's the it's the ultimate
wellness habit that goes uh
underutilized, you know, um because
um
first uh and just to give you some
examples that you know the sleep entry
period this liinal state where based on
measurements we can show you're kind of
awake, you're kind of dreaming,
sleeping. I mean, people like Edison and
Inception. Inception, the movie was the
falling chair was a concept based off of
Dolly or Edison where they'd be working
on some creative project and uh uh and
they'd he'd have a key in his hand in a
little metal basin and when he'd fall
asleep uh on the rock while rocking on
the chair, he'll fall forward, the key
would drop, and then he'd write down his
thoughts. He felt that there was
something that could be extracted from
that dream entry sleep entry state.
Lucid dreaming is something you know we
could talk about later but that seems to
be something that people report wellness
with people athletes people who are
visual spatial tend to have more lucid
dreams. I think that's an interesting
thought that we can um uh we can learn
that ability. There's a little bit of
sleep disruption about it. And then when
we sleep exit, which is a time I use
quite a bit, is I have the luxury of not
always hitting the alarm and I take
those last 5 10 minutes of thoughts and
I write them down first uh before going
on social media or looking at my email
and that seems to be an idea generator
for me. I think there's sort of those
practical elements that you can do. But
if for me just at a philosophical level
when my brain with my memory with my
imagination not somebody else's memory
not somebody else's imagination
>> runs in a different mode hyper emotional
hyper imaginative and something leaks
out of that that I can hold on to I
think it's worth taking a look at and
even just the process of reflection I I
think could hold some insight but I
would tease that out it would be that
the dreams that leave a strong emotional
residue do with a a central image. Um I
think it's okay to say why did I have
that dream? You know, be your own
therapist in that capacity because it's
coming from your imagination and your
mind. The concrete example I will give
is some people who are feeling well,
feeling like they're coping well, will
have a return, will have nightmares pop
up in their lives which serve as sort of
a thermometer. And so the nightmares uh
if they're progressive like headaches,
occasional nightmare is is whatever it
is, occasional headache is whatever it
is, but if there's a progressive uptick
in nightmares that can happen while the
patient is having the person's having
such a a fantastic life during the day.
So that can be sort of a a warning sign
or a signal that maybe you're not coping
well. So I think we're just starting to
get into those features of maybe
people's dream life should be part of
the vital signs. When I started training
it was like blood pressure and
temperature. Now we ask about pain, we
ask about wellness, we ask about living
situation at home. I I don't think uh in
the world of mental health it would be
it would be uh a stretch to start asking
and and engaging people with their dream
life.
>> Are dream experiences predictive of
something in health? You mentioned there
an uptick in nightmares across the whole
board. Somebody's dreaming more,
dreaming less. They remember it more.
They remember it less. More lucid
dreaming less, whatever. More
nightmares.
>> Are there any correlations between that
and someone's overall health?
>> Good question. The dream pattern related
with overall health uh would be
nightmares. Um so two types of
nightmares. Pediatric nightmares we
talked about age four five six which I
think are cultivating the mind they
don't really lead to nightmare disorder
where the next day is ruined and then
nightmares in
uh in adults they can happen once in a
while that doesn't seem to be a problem
but four or five% have nightmare
disorder where it disrupts the next day
and in in that situation whether it's in
PTSD or whether it's in trauma or
whether you're going through a difficult
situation tracking nightmares their
uptick or the improvement can be sort of
a a measure of how people are doing. But
as far as uh what I've read about dream
recall, dream patterns that changes
throughout our lives. So uh a lot of
adults say they don't remember many
other dreams. My cancer patients when
they get to end of life, uh they tend to
have these things genre dreams are
called end of life dreams. They tend to
be of reconciliation. They tend to be
more hopeful than you would suspect
after getting surgery and chemotherapy.
So your your dream p within our lives
from nightmares to erotic dreams uh to
the way we dream as adults to drugs that
change the way we dream and how much we
remember all the way to end of life
dreams. Uh if you don't think you have a
lot of dream recall now that doesn't
mean it won't be there for you. It can't
be cultivated. You just have to track
dream experiences and and prevalence
throughout a whole lifetime and you
start to see uh that they come in waves
which I find which is you know which is
interesting.
>> How real is dream interpretation?
>> I don't think it's real at all.
>> I mean because I you know I mean I can't
do it for myself you know like
>> so what hope is there of a lady in a
shawl being able to do it on your
behalf? Well, I mean, I think just we
have to look at it conceptually. I think
we were just talking about that. It's my
imagination. It's my memory. So, like,
let's how do you know what this snake
means to me, not just what it means to
me, what it meant to me 5 years ago. I'm
not the same person I was 5 years ago.
Like a bridge. Let's take let's take a
bridge for example. For some of my
patients, it's uh you know, uh they
might be thinking about suicide or it
could be reconciliation with a loved
one. It could mean so many things within
that context. How can a bridge for you
and me mean the same thing? But past
that, a bridge for me means very
different things
within the context of my own life. I
don't think a static symbol can uh
reveal a dynamic mental life.
>> Well, this would fit in with your
perspective that it's kind of a
gymnasium training ground sandbox for
the mind. That
>> high intensity training for the mind.
>> Yeah. that we maybe we shouldn't give
all that much credence to it. Maybe the
brain is just kind of running away with
itself because isn't it strange people
have intrusive thoughts all the time.
>> Mhm.
>> Uh they see somebody stood next to the
edge of the road and they think wonder
what would happen if I pushed them in. I
mean I'm not going to do it but
>> not yet.
>> I wonder what would happen if I pushed
them in. Oh god this would happen and
that would happen. Wouldn't that be
thrilling? You go okay. Are you making
some sort of inference about the sort of
person that you are for having had that
thought? Most people would say no. You
know, I just have intrusive thoughts
that occur during the day. And you go,
okay,
>> can't go to jail for thoughts.
>> So your intrusive thoughts when you're
awake and conscious are not that
indicative of the sort of person that
you are. And yet you're telling me that
the dreams that you have when you're not
conscious are worthy of interpretation.
um that I've never thought of that
before. But yeah, we're we're prepared
to give
>> we're prepared to dissect something
which we have way less control over when
we're asleep. But then on the other
side, you know, the devil's advocate
position would be there are very few
windows that we have into the
subconscious. The subconscious can often
tell us things about ourselves that
maybe we have repressed, not been
prepared to feel. And perhaps there is
some deeper wisdom to be gleaned from
when we're asleep. I agree with that,
but I don't agree
that, you know, um the lady in the shaw,
>> I don't agree that it can be uh made
universal,
right? I dream of a bridge. You dream of
a bridge. And it's filled with emotion.
It's a vibrant bridge. Okay, go ahead
and explore it. You explore it for
yourself within the context of your your
life and I'll explore it in the context
of my life. For me, it might mean
suicide. For me, it might mean San
Francisco where I went to college. For
you, it might mean something else. So, I
think the explor the the that the dream
residue being a window to our own
individual at that moment subconscious
hyperotional, hypervisual, hypersexual
state. Yes. But a symbol that captures
it uh between two people, let alone
between your former self. I just don't
understand how that can happen
conceptually.
>> What about erotic dreams? What what have
we come to learn about fuels?
>> I mean, why not? I mean, the it's
firing. I mean, you know,
why not that I mean that's uh it's this
is that was chapter three because
remember we're talking about like I
wanted to hit everything up up right off
the top. Why we dream? Nightmares.
Really? Nightmares and then erotic
dreams. Um
it's fascinating because it's another
thing that happens before the erotic
act. Kids don't have kids have who have
never seen a monster and have a puppy.
They'll have nightmares that are wild. I
mean what? That's that's that's coming
that's descending through our
psychological inheritance.
Erotic dreams, people have them before
the erotic act. It's almost like an
instruction guide. And and what's
fascinating to me is the there's not a
lot out there
when you go from sexual dreams to erotic
dreams, over 90% report having them. The
terminology, I don't know. I think it's
more inclusive. So when you start uh
when you do surveys in other cultures,
they're more willing to sort of say yes.
The term seems to be more It it's easier
for them to say yes to that,
>> right? Okay. Because it's
>> a little less porn vibe.
>> Yeah. And it would also imply maybe
>> hugging, cut, kissing.
That's not
>> exactly. They're not doing it with their
partner perhaps.
>> Well, and then the next thing is when
you ask and as we get into more online
surveys, this is going to be great. And
more people are included, but like 80%
report infidelity
and then the infidelities with a small
group of people like a repugnant boss or
like family. It's weird. the tribe, the
characters in the characters in in the
uh the you know the the cast and crew is
narrow,
>> the acts are wild. And so when you take
that data, healthy relationships have
infidelity dreams, unhealthy
relationships have infidelity, that's
those are sort of the surveys out there
and that that leads to a lot of cool
conversations. But what from a
neuroscience point of view is um this
the part that really trips me out is um
is is that around the time of erotic
dreams even before you know the
pituitary is dripped the hormones that
release all the hormones that cascade in
our body that leads to the sort of
changes of maturity is that the the same
fingertips that do touch can now do
caress. Yes. And it's not like a new
nerve got built in there. It's the
capacity to perceive sensuality
changes where the the sensory nerves
land in the brain. It goes to the
opposite side to a motor sensory strip
in the in the sensory region. So around
the time of erotic dreams
um we develop the ability to have
erogynous zones where a light touch on a
back can be a turnon rather than just
bumping into somebody in the subway.
that capacity doesn't really exist at
age six or seven and no new nerves are
being deposited.
>> It's a perceptual change in the brain.
>> That's interesting.
>> Yeah. So to me I I I like thinking about
I don't have I don't have any big
answers for that. I just want people to
walk away from that and say so th those
those changes the ability to be aroused
happens around the time of erotic dreams
and often it's before you're actually
mature. So it just seems to me again
that erotic dreams are arriving almost
universally in adolescence to prepare
for the act of procreation and to create
the drive in our mind that that we later
carry out in our bodies.
>> That's that's the way I see it. I wonder
whether I mean this is almost certainly
going to have been the case throughout
history. If you've got a particularly
um prudish society, Victorian England,
uh
>> they still get it popping. Well, of
course they you're not going to be able
to, but I I wonder how many people that
had these erotic dreams back then
would have
there would have been a real source of
shame
>> for them because I'm my my I'm I'm I'm
cursed. My subconscious is contravening
the norms of my culture and and God is
looking down on me. Especially if you're
told that, you know, God is watching if
you masturbate. God is watching who
you're attracted to. Uh, you know,
infidelity is one of the worst things
that you should ever do. You should be
loyal to your husband or your wife. And
uh,
>> and these dreams are like 80% infidelity
and it's all with people around you.
>> It's your boss. You know what I mean?
>> It's the boss you hate. Yeah. Yeah. I
think it I think it must have led to a
lot of inner conflict. Mhm.
>> And so that when I when I write about
erotic dreams and you look at it in
different cultures, you know, my feeling
is this is a this is a way that our just
like we learn to walk and talk,
nightmares do something because they're
a universal dream. Erotic dreams do
something. They happen in all cultures.
They've happened over hundreds of years.
They're happening with internet porn.
They're happening in Victorian ages. And
that to start really start to think of
the patterns the patterns of our dreams
are not infinitely wild.
That's the and then and then what really
teaches me is the patterns of our day
are not infinitely wild. We build and
break habits in similar ways. We fail in
similar ways. Like the brain is not
infinite. It does have some uh some
boundaries in the way it works in the
>> very least guardrails.
>> Yeah. or for example dreams are not
infinitely wild in the sense that you
you don't do math in your dreams so
there is at least one boundary right and
then uh they tend to have certain
patterns and and now I'm using that to
think about that we fail in different
ways while we're awake in our lives and
if you look at 10,000 people the ways
that people fail and succeed also start
to follow some patterns that I think can
guide us to like hey our brains and
minds work a certain way
>> and and when we learn about that then
you can say where are we in this? how
how is our thermostat is is a victory
today just getting out of bed or and not
saying hey wellness I got to be I got to
feel well or just I got to get out of
bed and get on the bus and get to the
cancer center like so I want to
personalize that whether you're the
addict this is this is just a side rift
man but whether you're like there this
uh there are these people in recovery
really good with horses in the Kentucky
Derby whether you're into horses and
racing or not but somehow the horses can
tell somebody who's been through
something and has earned and trained
themselves to be calm like they have a
better rapport with the animals.
>> No way.
>> Yeah. Yeah. It was it was featured when
it came out. And so then and then
there's like then you know like I was in
San Francisco and I saw this person
really struggling to not use you know
just really just fighting that. And then
I got a buddy in London who runs like
this north uh Saharan seven marathons in
a row, you know, just to show everybody
he can. and when he's pushing to
complete that seventh marathon or that
the person using is really pushing to
not inject I think it's actually the
same praying processes and patterns that
are working inside
>> and if we can learn how those work how
those can be deployed how those falter
then we have a universal toolkit and
that's what this dreaming book that's
why I told you earlier was like it's
really important for me is because it's
helped me actually understand that If
the dreaming brain follows patterns,
which seems infinitely wild, right, that
you brought up, then okay, so then our
waking brain, we we follow certain
patterns. Um, and we're not incarcerated
by it. But if we learn those rules,
uh, rules of survival, rules of our of
of how our day can be empowered, or
watch out for that booby trap and that
falter, and watch out for this
attentional magnet because it's going to
trip you up. like you could have a uh
you could have a toolkit, you could have
a guide book to your own to your to your
to your own mind and I that's where I
want to take things uh going forward and
that's what this dreaming book has
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wisdom. That's drinkag.com/modern
wisdom. What do you make of the
prevalence of the repugnant boss in
Erotic Dream?
>> I don't know if it's a power dynamic,
you know, or it's uh,
>> you know, I I don't know. Or the family.
And I mean, my idea was sometimes um,
yeah, the repugnant boss. But what the
the the
narrow list of characters, I thought, a
hypothesis. Um, again, there's many
things we can talk about that can't be
proven, but evolution had bottlenecks.
Like, there were times when,
like, it's crazy if you think about it,
like how many different homminid species
there were at one time. And, um, maybe
homo sapiens were down to a few hundred
thousand or a few thousand at that time.
>> And maybe it was an evolutionary
advantage to only procreate within the
tribe. Like, that's a very hypothetical
scenario. But there's there's a field
called evolutionary psychology that our
cognitive archaeology that the way we
think
>> uh was an advantage that led us to uh to
thrive in competition with other other
homminids because you know people like
oh bigger brain the brain is shrink stop
that Neanderthalss had bigger brains but
something with our minds was the
advantage it wasn't just the size
compared to Neanderthalss and this
that's why I of like evolutionary
psychology that and the way we're
thinking now is something we've
inherited that was advantageous hundreds
of thousands of years ago but we're
still but we have to now adapt that to
the modern life.
>> Okay. So if we're thinking adaptively
here I'm also a huge EP fan. So, um,
>> if we think adaptively, the repugnant
boss, uh, or or the the family member
very well, maybe
we're not particularly well used to
having 200,000 people available on Hinge
or Tinder or or in our local city that
are our age and hot to trot, there's
usually only a very very small group of
people that are here. And perhaps the
sleep dream of that is, well, what if I
test this out? How what how does that
make me feel? What does that mean for
me? Because there aren't that many other
people that are available and probably
should see if this is actually going to
work or not. Oh, I mean I mean it's
possible. I mean, now um as far as the
characters in erotic dreams, whoever
writes this book next
is going to have a lot more surveys from
a lot of different types of people
speaking a lot more openly about these
things.
>> And then they're going to have to figure
out like, you know, I mean,
celebrities are part of the erotic
dream. They're considered part of the
tribe like Brad Pitt or whatever. Like
celebrities show up feel
>> something to do with status maybe
>> or familiarity that you see them. so
much you feel like they are potential. I
I don't know. It's it's we're just
riffing. But I'm curious to see that
with with social media and stuff, how
influencers do they show up in a similar
capacity as conventional celebrities
that I grew up.
>> Let me let me warn you right now. You do
not want the pillar talk of a podcaster
uh in your dream or not. You know,
>> people going to call in and they're
going to write in.
>> No, thank you. No. Look, look, you went
>> Repugnant boss, Chris.
>> Yeah. You slept with a podcaster. What
did you expect to happen after cuttinged
three hours and he's still going he's
still going on about the biggest gun of
World War II? Will you shut the [ __ ] up?
Like, hey, look, I mean, you you asked
for that. You knew what you were getting
into. Um, on the on the erotic dreams
thing, I don't know whether we have
enough longitudinal data to work this
out. I would be fascinated to see what
impact the prevalence of porn has had in
changing the sort of erotic dream. Uh,
men cycling through even more partners
in one sexual fantasy. Um, are they
being influenced by what they see on
screen? I certainly know that if I read
Well, if
>> that's a massive book, get just 10
years. Somebody just need to rock that.
>> I I like to read uh fiction before I go
to bed. And I've been I have an
admission to make. I've been getting
into chick stuff. A lot of chick stuff.
Uh Freda McFaten, The Housemaid,
Housemmaid's Tale. Um, uh, Alex Michael
Lades who wrote, uh, The Silent Patient.
It's like thrillers like
>> written by chicks, but not necessarily
only for women.
>> Really good. Insights come from
everywhere.
>> Easy, easy reading. Usually woman in her
early 30s that's kind of looked over who
fixes some sort of crazy murder thing
that happens that impacts my sleep like
[ __ ] dude. Like I go to bed and I've
got but it's usually
interesting. It's a particular So you
think, okay, if the thing that I read
before I go to bed, I'm also watching
the tour to France Unchained on Netflix
at the moment. For some reason, I'm not
having many cycling dreams. If these two
things are happening, we have to assume
that people who horn a lot
>> the volume,
>> how is that not impacting dreams? I
think that's the I think that's the
experiment uh that's uh that's ongoing
and somebody
younger
than me will see that that's the
opportunity here to look at that and in
this in the context of dreams the it's
super physiologic stimuli is another
concept like
>> you know the the you can't look away cuz
it's just so it's just like a cod up
version of something and so you may have
some finesse and emotional regulation
and you may be able to sort of in your
own competition at wants to be like I'm
not going to look over there because yes
I feel desire and lust for that that
image but that pops up once or twice but
when it's just like on loop and you
can't I'm surprised it's porn addiction
is only 5%. All right, given just the
supra physiologic uh stimuli that it is.
Um but yes, the impact on dreamscape,
the modern world's impact on dreamscape
is as big as the when there were rumors
that when black and white television
went to color that dreams also became to
color. There's some urban legend about
that. Like I mean the world was in color
but when when color magazines and and
and color TV came out there are small
reports that our dreams were more in
color.
>> Wow.
>> So that's a but the point is whether
that whether somebody can further
explore that or not but right now this
is this is a this is a PhD thesis for
somebody right now if they want to run
it is
>> how unsurprising that the things you
consume will influence the way that your
subconscious works at night. But
sometimes not,
right? Like it's it's an inconsistent
process of feeding your dreams.
>> And that's what I like about it is that
you think like this you you think your
dreams are only going to have the thing
that you're worried about and it
doesn't. So it has it's metaphorical
like your you might have a lot of
anxiety about uh something and then your
dream is filled with anxiety. But it's
like it's like Vietnam veterans when
they were going through divorces, they
would have their PTSD come back. They
weren't they weren't dreaming about
fighting with their lovers or spouses.
So dreams
arise in a way that's metaphorical and
requires interpretation
uh by the person who's having the
dreams.
>> What do you think that says about where
the inspiration for dream material comes
from?
>> I think it's a constant it's so
so I think during the day we are just
stay with me now. Um, if we took a if we
took a brain, we flattened it out and we
said they were continents, right?
Thinking of the brain as this spot or
that spot. Sometimes if we injure a
certain spot like a nail, I used to take
care I did a lot of trauma nail gun
injuries. They come in with like a nail
stuck in, you know, or they'd have a
fall and a blood clot would come out.
You would say you take out a certain
part and they would lose a certain
capacity. You say, "Oh, this is what
does this." It's not like that. It's
like Heathrow or London. You know, if
you have an issue at LAX, it's going to
disrupt something globally. But it's not
that LAX does flights. LAX is a hub that
controls flight throughout the planet.
Similarly, there are spots in the brain
hubs that control broad processes
throughout the brain. And and what I
like about it is that these injuries
have informed us about how how the brain
works. And when you have an injury in
that dorsal lateral prefrontal cortex,
which is these little spots here that
that's the conductor of your whole brain
while you're awake, those people
struggle with math. And so it's okay, it
plays a role in that. And if you flatten
out the brain and you have these
different continents and lobes and
structures, hypothetically, you have
certain parts that are ramped up during
the day during executive network.
They're they're not in one area. They're
connected by a lot of things like like
where's the economy? I mean it's in the
cities in Wall Street. It's everywhere
but there are some hubs. So the
executive network is one it's like like
in Las Vegas where Bellagio where those
waterfalls go up. Think of the executive
network as those neurons and their
connections. They're like 51%. They're
running [ __ ] right now. And the
imagination network is 49.
And and and when you dream it it it kind
of flips. you have 49 51 hypothetically.
Okay. But when you're when the when
you're daytime and it's executive
network, you're still pulling from
imagination to to run to get the task
done. You're still think if I went left,
if I went right, it's called
counterfactual thinking. If I go this
way, last time I got hurt, you know,
you're still imagining
plus e executive network. And what what
happens with dreams is when the
executive network falls back, your brain
uses imagination in its own mental
workspace. Uh and the biggest example of
that is dreaming. So think of the brain
is always on and there's always uh
there's always there's always a balance
between executive network and
imagination network and and the examples
of the most dominant time when your
executive network is happening is under
threat when you have to navigate a
crisis and the biggest example of when
your imagination network is is most
dominant let's say 54 uh to 46 is when
you're dreaming but everything in
between is a dance between idea, you
know, execution and idea. And what I
like this is this is just a side riff
like they did this thing about analyzing
uh poetry or book cover designs and they
would put these people in fMRI machines
and the idea generation is mostly
imagination network. But to figure out
if you came up with a good idea, you had
to toggle back to dominant executive
network. Otherwise, you got a bunk idea,
right? Mh.
>> And so the what I don't want people to
walk away thinking that we're liinal
states that we're all one or all the
other and it's a there's a thermostat in
our life and how to cope. But there's
also a a balance of of executive network
and imagination network. And there are
things creative people do to bring in
the imagination network. But uh
imagination requires executive function
and really great executive function
still requires imagination. What are
some of the ways that people who want to
activate their imagination network more
effectively when they're awake can do
that?
>> Um, all right. So, I I got some stories
for this one. There are some examples
that speak to again a damaged executive
network liberating a lot of imagination.
One example is alcohol. It dampens the
executive network and some people feel
that they're more creative on alcohol
and it's dose dependent you know not 10
drinks not one drink I mean alcohol has
to be really handled with care at
different doses it makes you feel
different things uh number two
fronttotemporal dementia that Bruce
Willis has these patients in Alzheimer's
clinics when they have a certain injury
to that part of the brain there are
publications if people go on and look it
up they show them and they're like
artistic abilities they can paint a lot
better dementia and injury to the
executive network leads to a liberation
of uh of of hidden artistic like
painting drawing talents. So those are
two examples. Some people get hit with
lightning bolts and even if it's one
person the the electrical shift can
release um can change that executive
network to no way.
>> Yeah. Yeah. I mean they're they're out
there for savants so people could so
when I say this I want people to look it
up you know uh uh and that's also one
flew over the cookies cuckoo's nest
where that movie made a portrayal of
shock therapy as very negative and it
generally was but now we create we send
in electricity and create a seizure to
break people out of suicidal thoughts
and stuff. So there are a lot of thing
and those people sometimes have more
creative ideiation. So we know that
there are hidden
uh hidden creative abilities in all of
us and the executive network is is is
reigning them in to get the task done to
to drive on the freeway to be on the
tube. So how can we extract those? I
would go back to sleep entry um where
that's a window where Salvador Dolly
thought you have good idea generation.
Sleep exit is also an I is a time where
the executive network hasn't fully come
back online. if you will. So, your ideas
will I have a lot of ideas during that
time. Bad ideas, good ideas, but it's an
idea generator. And then during the day,
what you have to realize is you're not
going to hit undirected thought is
actually the thought you want when
you're trying to be creative. It's hard
to have a triple espresso and then drop
creative stuff. Uh it's it's the liinal
time waking up, meditating,
um exercising,
uh focusing on something like a flow
state partially but not, you know, not
exclusive,
>> driving, doing the dishes, playing
pickle ball,
>> but partially engaged and and then
something and then some and then it you
can't demand it. You have to cultivate
it. You can't liberate.
>> You can't white knuckle creativity. It's
highly highly irritating.
>> Another espresso. Let's let's
>> Yeah, run it back. [ __ ] it. Um, yeah,
that's that's certainly something I
found to be true. Um, sitting down and
demanding yourself to be creative is a
reliable way to ensure that you're not
creative.
>> You have to flirt with it. I mean,
that's why it's not that's why it's not
a gift everyone has, but it can be
cultivated. You know,
>> what's you you mentioned there about
some of the transcranial
electric stuff as a neurosurgeon person
in that world. What do you make of
what do you what do you make of this
sort of new revolution? I know that uh
depression, anxiety, some compulsions
are being treated with this now. Um
>> Mhm.
>> Yeah. What do you what do you make of
this? It's real, right?
>> But it's also very easy to go on Amazon
and get one for $4.99 where they got the
little headband and being positioned in
the same way. So the stuff where it's
real is rigorous. It's intense. It's at
massive elite centers. Yep.
>> And a week usually 30 days of
backto-back treatment as well.
>> Yeah. And they and not a 30-day refund
like on Amazon, right? So every time
I neurosurgery was neurosurgeon was a
funny word. Um
>> we have to be able to talk about things
like instinct and hunch because that
leads to the fullest capacity, right?
Smarts plus instinct. Who doesn't want
that? Sports has the best thing like you
know under pressure how people perform.
That can't that can't be white knuckled
either. The the brain has to be thought
about in scale. You cannot answer all of
these questions with the brain. Like
people talk about it's like you can't
it's not a homogeneous organ. It's not a
liver. If you dice up the liver at
different areas that and you put it on a
magnifying glass, it's the same cell
essentially for the most part. The brain
has so many different cell types, so
many different architectural components
floating inside a u you know a it's
buoyant. It's floating or stride liquid.
It doesn't actually sit on the skull,
you know, and like so it's it's an
ecosystem of little electrical molecular
machines like tiny jellyfish that are
spraying electricity and chemicals at
each other. And as we talked about
before with those stickers, you can
record electricity.
um you can also deliver electricity and
that would be shock therapy and now
what's less disruptive is delivering uh
using magnets so for people who are
familiar with physics I'm not I took all
the classes to go to medical school but
electromagnetic fields they they can
influence each other so you can pulse a
magnet through the skull and it can
change the local electricity of a
certain region so you can actually uh
put a magnet on the surface
no incision required. Um, and pulse to
the motor strip and make somebody's arm
move
because back to it's an electrical
currency that leads to uh
>> dreams, you know, it's measured at night
with dreams. It can be it can be
tickled. And so now Stanford is doing
some good stuff within other places is
well, what if you uh what if you have
obsessive compulsive disorder? somebody
else makes the diagnosis. The term is
not used casually, let's say. It's not
like, oh, I'm obsessed. But somebody
really is like, man, I turned that
doororknob 120 times today.
>> So, they're looking at the the pulse can
be used to dampen the dorsal lateral
prefrontal cortex. Oh, and it can be
used to heighten. So if you pulse that
area every day for 30 days and you
dampen it a little bit and at the same
time somebody gets therapy and you do
cognitive reappraisal like the the the
parts of therapy that I like are some of
the ways where you're basically training
yourself uh and you say hey that's not
dirty don't don't worry about it or that
door is locked you don't need to wash
your hands 80 times a day like you you
you've been struggling with that fight
the whole time people with OCD they know
they shouldn't. And now if you pulse
that area that's kind of made it, you
know, difficult for them to control,
that combination is leading to results
that we haven't been able to find by
just giving medicine.
>> So it's real. But the thought that
you can buy this and then do it for
yourself,
>> self- administer.
>> Yeah. Or with with
um with a with a device that looks the
same but is not delivering the same
technology. But that that is the future
of mental health is a combination of
therapy, magnetic pulsing, occasional
medicine, and that as a cocktail, not
just like three different types of
anti-depressants, which were helpful in
for people, but a mixture of talk
therapy, a mixture of exercise, talk
therapy, magnetic pulsing, all
non-invasive.
And if you can get a 10 20% improvement
in what we're already what was going on
right now, I think that's fantastic.
Before we continue, if you haven't been
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That's functionhealth.com/modwisdom.
You've triggered dreams while people
were awake during brain surgery. What's
that tell us about
>> do I mean this is how the I mean this
was a story back in uh I noticed in my
20s when I was in training. So um
um
so there's a thing you know some some
patients benefit from being woken up
with with their skull open in surgery.
This that's
>> how could you benefit from that? Because
whereas this dorsal lateral prefrontal
cortex, we kind of know where it is.
Whereas the movement area, like the hand
region, we kind of know where it is. You
know, just based on an MRI, it's
consistent in you and me and others.
Language is in a neighborhood. It's in
the left temporal lobe right around
here. And there is no uh there is no
specific address for it. It's different
in in both of us. And so to figure out
um where language is so you don't hurt
it as you're trying to enter the deep
brain through that area you have to map
the brain and let me and so what we're
trying to do is to get to it. So uh the
neurons the bodies of the jellyfish
molecular jellyfish are all on the
surface and then their their axons and
tentacles converge into the middle of
the brain. So the cortex, the canopy,
the treetops is where all the where all
the thoughts are happening, if you will.
Um, and so what we're trying to do is
identify the parts of the treetop right
here, the cortex, that when you stun the
activity in this tiny little area, it
doesn't lead to any any issues with them
talking or understanding. And this is a
this isn't just like they'll still be
able to text. You can you can hurt the
whole capacity of language. So, uh, the
only way to do that is to wake them up
in surgery. And there's a you numb the
scalp, you put them under anesthesia,
you open the skull, it's like ice
fishing. Uh, then there's a little
covering on the brain called the
duromat. It's like a uh it's like um,
you know, like a sort of a skydiving
parachute material. You can pick it up
and stitch it at the end.
>> You open it up and then there it is.
It's beautiful. It's stunning. It's
white, speckled with blood vessels. Um
and um and then you then you let them
wake up slowly over 30 minutes. Uh you
the propall is lightened and then
somebody engages them and you have them
count and sing and sometimes even play
the guitar. Like UCLA's got a YouTube
video of somebody doing that like bigger
capacities, right? Um not just like
pinch your finger but and so they'll
sing like they'll sing or they'll count
and it'll do it in multiple languages. 1
2 3 4 5 6 1 2 3 4 5 6. And then you'll
then you'll take a little spot, a little
electrical pen. It faintest bit
electricity. And the brain can't feel
when it's being touched. It only feels
through the nerves it sends out. So when
you dissect the brain on an awake
patient, they have no idea what's going
on. And you tickle the uh you tickle the
spot and they and you stun those like
collection of neurons there, maybe the
size of like a tiny pee, and they keep
counting. One, two, three, four, five.
and you say, "Okay, I can go through
this little piece to the deeper brain
and I won't hurt their language
abilities." So, you put a little white
piece of confetti on there or a number
>> and then you go next to it and then
you'll find areas that cause speech
arrest. You'll say, it'll be like 1 2 3
4 and you'll bud go 1 2 3 three three
three.
That's for real. You guys can look all
that up. That's been going on for 60 70
years. And he said that caused speech
arrest. You put a little red piece of
confetti. So at the end the surface of
the brain as you're going deeper looks
like Swiss cheese and you've you've
identified the portals through which you
can dissect to take out the deeper tumor
uh and not injure their language.
>> Why is language such an important
indicator?
>> Oo that's a big question. I mean I think
it's uh um I think it it kind of makes
us who we are. I mean it was sort of a a
differentiating thing for for mammals
uh is language and then all the
complexity that comes with language but
it it is housed in a neighborhood and
unlike the frontal loes uh there's not a
lot of redundancy.
So the motor strip is the same.
Apes, you know, humans the same.
Language, it's kind of a fuzzy address.
One frontal lobe can be injured with a
spike,
>> with a tumor,
>> and people are mostly fine. I mean, they
go home, they drive, they go to work.
>> So there's a maximum redundancy in these
the prefrontal cortex is a it's a it's
an important word. It's front of the
front. It's the the things that that
pushed our foreheads forward and it has
three very interesting components. The
dorsal lateral prefrontal cortex which
is mostly out here dorso up lateral it's
just fancy. Then there's an orbital
frontal cortex which just sort of sits
above the eyes and that does a lot of
like when people get injured there they
can't change their political views or
they don't get like social phauxawa like
there's a lot of complex social things
that happen up here with a lot of
redundancy and then language and
feelings of spirituality and stimulating
here where people like have nightmares
smell burnt toast that's temporal lobe
uh and that's that's a fuzzy area
without a lot of redundancy
And then the motor strip is a very
precise area. So there they're different
regions you have to learn how to dissect
around and through.
>> And some of them can have a little bit
of damage and you still function
relatively well. And some of them even a
tiny bit of damage and it's it's
wrecked. Yeah.
>> And that's the that's the craft is how
do I get to the deeper brain?
>> Um how do I which
>> without damaging anything that doesn't
have redundancy.
>> Yeah. How do dreams differ in people
that have got brain injuries or really
severe trauma?
>> Um, that's a good question. The
um the range of injuries vary, the range
of drugs vary. I couldn't I couldn't
figure out like the dreams on drugs was
just so wild. I couldn't find a pattern.
I mean, you know, people smoke weed. Uh
they don't remember much. So, are they
having fewer dreams or fewer less dream
recall? And then there were stimulants
and anti-depressants and all the
different combinations. I couldn't find
a consistent pattern for it to become a
chapter. I think that'll be for the next
author. And similarly in brain injury
um um there there wasn't really a
consistent pattern with exception to one
the
uh the phalamus is sort of like this the
pineal gland that they talk about being
the third eye. I mean we we remove that
melatonin goes away. and we remove that
and patients are fine. So I'm not saying
that people shouldn't believe in the
that concept and dart and third eye but
the pineal gland is essentially a vestid
it's like an appendix but the central
like the size of an egg there's
something called a phalamus which is
sort of the gate for all the sensations
coming up and it refineses the movements
going out when you have injury in that
area uh they tend to have a lot more
lucid dreams immediately afterwards. So
like like it's it's almost like uh
there's too much arousal permitted in
the sleeping state because the phalamus
is injured, right?
>> The gatekeeper has stopped keeping the
gate,
>> right? Cuz the gate is again nothing is
ever off. If there's an alarm that goes
off or you smell smoke, you're going to
pop up out of your sleep and dreams and
that what is let through. I used to do
all kinds of weird things like have
people sleep and they put their hand in
a glass of water or a bucket and see
what that changed. The point there is a
phalamus is uh is the gatekeeper that
lets certain things through. If that
part is injured, uh the lets certain
things through and says time to wake up.
There's an alarm. If you injure that
part, you get a more more lucid
dreaming. Awareness seems to creep into
the dreaming state uh a little bit more
readily.
Could you see in some ways the thoughts
that people have in their dreams being
more real or more accurate to their
sense of self than their waking
thoughts? They're unencumbered by the
executive network tamping everything
down. Their sense of self, the story
that they have arked together. This is
who I am and this is what it means to be
me. Uh I had a conversation with Dr.
David Spiegel about hypnosis
>> and it sounds not too dissimilar that
maybe in some ways we're liberated. So
yeah, I wonder whether yes, some of the
thoughts we have in dreams could be more
real than the ones that we have when
we're awake.
>> Well, um I don't know, but I will tell
you that um
some dreams require no interpretation,
right? You're stressed out about giving
a talk, you show up naked at the podium.
Uh your end of life dreams, those tie
up. But as we discussed earlier, let's
not hold dreams to a a standard we
wouldn't waking thought. like we have
all kinds of junk thoughts and thoughts
that we don't want to hold on to,
thoughts that don't reflect who we
really are.
>> Um, and I think similarly for dreams,
it's it's a wild landscape. What it is
is your brain in a hyper emotional,
hyper vvisual, hypersexual, hyper
imaginative state that is creating
experiences at the neuronal level. Not
at the you're paralyzed or you're not
living them out, but it's from your
memory. It's from your life story,
right? It's drawing upon all of that
imagination that's liberated from the
bank of memories and experiences you've
had. And I think in that way, it's
personal, this individual. And maybe
doesn't give a truer insight, but it
gives a different insight. So, you got
to think about your life when you're
awake, when you're waking up, when
you're falling asleep.
>> Hold on to that dream that that stuck
along stuck around a little bit longer.
Um, and just use all those portals to
put to stitch the story of are you
liking where you're at and maybe you
need to change or maybe you need to be
at peace with yourself.
>> I think the main thing that it makes me
think is that it's a reminder we have
way less control than we think we do.
>> I love that.
>> I think that's the main thing.
>> [ __ ] is firing. We are not driving. I
mean, and during the day too, right? I
think that goes back to the but if we
learn the ways in which at this time I
have less emotional regulation at this
time I have more emotional right like if
we knew it's not that we have a lot less
control but it's almost like riding it's
this like the stream of conscious like
there are some boundaries and you are
you are sort of riding on a river you're
being tossed around but you have some
you can drop a hand and control and
pivot and move around a little bit so I
think if it allow allows for uh failure
not to be permanent. It allows for
triumphs not to be permanent and allows
for us to say um that it's okay to not
have a linear goal of self-improvement
and growth mindset. Like to me it's
cyclical. Uh there's the winter in our
life. Victory is sometimes just getting
up. Victory is sometimes not, you know,
just not falling apart if you get a
cancer diagnosis or your child gets ill.
So I'm trying to come up with universal
ways of understanding how our brains and
minds work. So it applies to the the
elite uh 900 running 100 mile athlete or
the person saying you know I don't want
to use this Oxycontton that I got after
surgery. I'm trying to give this up. You
know
>> that it's the same universal processes
at play. It takes the judgment out of it
too. Going a bit more broad than just
dreams. Someone that spent a lot of time
looking at the brain. What are the myths
that are widely held about the brain
that annoy you the most? What do you
wish people would stop believing?
>> That's a great I I wish they would start
uh stop talking about it as the brain
as if it's a homogeneous
singular entity, the brain, the heart.
>> And I think it's uh I think it requires
just one level more. Um, and the way I
would say is I'd love for people to have
a sense of scale in their explanations
and podcasts and stuff. Is it at the
neuronal level? Is it at the network
level, executive network or uh
imagination network? Is it at the lobe
level, the anatomical level, temporal
lobe and language? Is it at the global
electricity level?
Seizures, dreams. And so when people
say, well, the brain prefers this, the
brain thinks this, like the I it doesn't
make sense to me because um it's not
descriptive of the tremendous diversity
in this ecosystem in our skull. So I
would I would love to see one more level
of not proof but little precision,
>> depth of explanation that goes beyond
the brain as if it's like muscle or
liver.
>> Yeah. Yeah. Yeah. Yeah.
>> Right. So that then that way you'll know
if people have really thought it out. Uh
that's one. And then the then number two
is this myth that we only use 20% of our
brain. No, I mean the whole brain lights
up. But to do one thing, we may only use
20%. Because it's really an energy hog.
So the brain wants to be efficient and
fall into patterns. Um and the and the
last one is that it's limitless. You
know, your body's limitless. Your your
mind is limitless. Actually, no. It's I
I think you can be closest to limitless
in your behavior.
Um if you realize that there are
patterns and proclivities and tendencies
that all human brains and minds have and
to try to identify when somebody does it
well, what are their coping strategies
when somebody's struggling uh the way in
which they falter with their goals? Um
maybe I don't I'm not falling apart now,
but there's there's a lesson there for
me. because I don't know what's coming
down the road. I haven't gotten knocked
down yet like and that's called
ecological validity where it has to
constantly be tested in real world
scenarios. So to me the the learning
that the brain is not limitless
limitless and the brain creates a mind
that is reciprocal brain makes the mind
mind can change the brain a little bit
and then the biggest conundrum is why
the mind doesn't always translate to
behavior. you're like convinced I'm not
going to do this or I'm going to do this
and you just can't get it done. That
bridge between mind and behavior is also
another an area that I'm looking at. And
that's where the coping strategies go.
Rather than saying, oh,
don't drink, don't smoke. It would be
nice to say when the thought of smoking
a cigarette comes in your mind, these
are the processes going on. Break it at
the cognitive level with step one, two,
three. Avoid the intentional magnet. Do
this. Don't look at it. Definitely don't
let that smell come into your nose.
Okay, now it's in your body. You had a
whiff of smoke that your partner's
having. Now your body's jonesing for it.
You your hair is sticking up. Bring in
these strategies here. Somatic
therapies, deep breathing like to know
the ways in which we falter and then to
apply strategies because the brain has
uh uh is not limitless. It it falters in
a certain way, triumphs in a certain
way. So a little bit more prescriptive
to the way what stage in your you know
failure or triumph you're at would give
a little bit more precision to rather
because it could it can get
overwhelming. I would never tell my
cancer patient like you know just be
well or you can do it. They have to be
coached through the process. So I'm
trying to come up with a universal
toolkit to understand this is what I'm
feeling. This is the way most brains and
minds and people falter when at this
stage of addiction of desire and at this
step I want to use these strategies.
Okay, now I'm going to get the
cigarette. Okay, now I want to use
mitigation.
Give away the pack, you know, like but
not to just give a global strategy.
Don't smoke.
Don't smoke. But if you're being pulled
in that direction, here's the game plan.
Uh, that's what I want to build a
universal toolkit.
>> Do you think the neuroscience industry
is overselling some of the new tech
that's coming along? fMRIs,
>> brain scans of all different types. We
can detect onset of Parkinson's, CT scan
with contrast, all of this stuff.
>> Are we
are they making promises that the sort
of insights can't cash?
>> Mhm. I think so. It started like 20 30
years ago. We needed these scans to do
surgery to do brain surgery. So I tell
you this is another story. My professors
they when you had a blood clot they
would see like somebody's eyeball was
you know pupil was big and they would
call it exploratory tffonation with a
hand drill just start with the patient's
family's consent. 30, 40 years ago,
there were no CT scans and they would
just make random holes till they hit hit
blood like drilling for oil. Then a CT
scan came out and changed everything.
You could see which side the blood clot
was on. It's fantastic, right? They're
coming out of hospitals for
neurosurgery. Then we try to figure out
like function and that's where fMRI
started and because MRIs don't have
radiation, you can elect to be in there.
You can get MRI every day. CAT scan has
radiation. And so neuroscientists
started putting people in there. And
what I would say is what's happened is
the term is being thrown around brain
scans. But u the information nobody's
explaining it. Um that this area is
activated. But what if you activate the
area that uh you know stops a function?
That's different than activate an area
that grows a function. Right? So the
there's a modulation of the brain. you
don't not all activation is good not all
inhibition is good right and so that
those nuances are not not getting out
but the term brain scan can be used by
any author now and I'm not saying that I
mean everybody's an expert in the brain
right because we have one so I don't I'm
not saying that we should limit that but
the question should be one step further
that and what what is the meaning of
that a brain scan shows this and and the
way to understand in my opinion what the
meaning is is to ask how is that
experiment set up
right like just to say so you have a
thousand people who think of puppies in
a fMRI and then you have a thousand
people who don't think of puppies and
think of snakes in fMRIs and then you're
looking at the differences puppies
effects on mental health versus snakes
effect on mental health That experiment
can't be set up cuz you can't stop the
person thinking about py puppies
thinking about snakes and you can't
really control the person thinking about
snakes thinking about puppies. There's
no way to set that experiment up. So
when it says brain scans show this, I
think if I were an interviewer, I'd say
well how is that experiment set up? And
I think that way we would get past some
of the fluff that's out there because uh
it has there has to be an experiment
that justifies the answer and then just
throwing out brain scan I don't think is
enough. M what role does lifestyle
really play when it comes to cognitive
decline?
>> Massive.
>> I'm seeing a lot now. I'm big behavioral
genetics stan as well. I think that
heritability has got a
feted past. Uh but it's real important
and I think that more people should
learn about behavioral genetics than do
I think it's there's a lot being laid at
the feet of of lifestyle because it's
something that we do have control over
in a meritocracy.
uh where people feel like they want to
be able to author their own life. This
idea that you are being puppeted by some
stuff that happened literally before you
were born, like as you were conceived,
um is very disempowering as an idea to a
lot of people. But I also think it's
super informative and if you can kind of
get past the initial discomfort of
there's some stuff that I didn't choose
that I'm at the mercy of. Um but on the
flip side of that, lifestyle as well. So
talk to me about cognitive decline and
its contributing elements, lifestyle,
genetics. How do you come to think about
it?
>> DNA is not destiny. Um
especially when it comes to the brain
and mind like I mean DNA might be
destiny for like heart attacks and stuff
like that or certain there are certain
medical conditions that are very linked
to genetics epigenetics but um whether
you have uh a proclivity
uh or tendency to have Alzheimer's or
dementia or not whether you want to
stave that off because you don't want to
know based on a new Alzheimer's test or
whether you've been given a diagnosis
and you're trying to work through it.
The treatment is all lifestyle and
behavioral. The medicines are limited.
They're um they exist for early
diagnosis and Alzheimer's, but the
treatment is all lifestyle. The way I
the way I think about it is five five
key things to do or or a handful of key
things to do. Um is one, you got to keep
the arteries open. We've been talking
about the the the beautiful brain. You
have four arteries coming up. They they
get into this beautiful branching
pattern. It's exquisite. Parts of them
loop over each other. Looks like a
chandelier. We call it the candalabra.
And they get narrower and narrower. So
you got to irrigate the flesh. So
whatever is good for keeping heart
arteries open and kidney arteries open
is also good for keeping brain arteries
open. Exercise.
>> Yeah. Or taking the the anti-
cholesterol pills that are long
established and mostly safe. Like pretty
safe, you know. So exercise. Yeah. Um
but exercise does a couple of them. So,
you got to keep the plumbing open to
irrigate these neurons. Um, number two
is
uh
you have to eat a certain way. And I
know there's a lot of diet stuff out
there and that's a whole theme. But the
thing that over decades has been proven
uh to preserve or even increase
cognitive health, cognitive function is
um is the mind diet and which is the
closest thing to it is pescatarian.
It's mostly plants
fatty fish and the reason fat so I like
to take it one step one step deeper. The
reason it's fatty fish and omega-3s is
you mentioned the word mileelin before
and so the little the the neurons and
the axons. The way they make the
electricity communicate faster is that
the cable is wrapped uh with a fatty
sheath that's called myelin and then the
electricity actually jumps uh across the
little gaps they have and it goes faster
than if it is not mileelin coated. Uh
and thought can actually deposit myelin
preferring that thought to happen again.
uh that myelin sheath is made from
omega-3s. So you there's a specific fat
that's needed for myelin and that's
omega-3s and fatty fish. You can get in
in flax seed and other things too. So
keeping the plumbing open, giving the
brain the material it needs. Now we're
at the at the scale level, right? Okay.
And then you then you go in a little
deeper.
Um the timing of eating is interesting.
I I do think there's some pretty strong
neuroscience evidence of intermittent
fasting. I know there a lot of diet
things out there, but
>> skipping if who if you have the luxury
of skipping breakfast,
>> skipping going 16-hour windows will uh
if you don't eat, you're not going to
just drop dead. And the brain the brain
is a uh uh a hybrid vehicle. the brain
can live off of neurons can, you know,
thrive and and use glucose or ketones.
And so after 16 hours, your liver will
will turn out ketones if you haven't
eaten. So that's how you live past, you
know, the 16 hour window if you don't
consume anything. And that switching
back and forth
um in intermittent fasting, the
cognitive test now, now we're getting
from flesh to mind. Um, uh, people seem
to have more focus. People seem to have
more, it's not about weight loss, but
intermittent fasting, it's letting the
brain have glucose and ketones couple of
times a week.
>> That's interesting. So, your suggestion
here is that all ketones, someone that's
doing a full ketosis or carnivore style
diet or somebody that's doing a classic
sort of omnivore style diet, which when
you're grazing, typically you're not
going to drop into ketosis unless you
forget to eat carbs for a couple of days
or something. Uh you're suggesting that
there is a principal brain benefit and
neurological benefit to the switching
between these two fuel sources.
>> Correct. That's interesting.
>> Weight loss is separate.
>> Yeah. Yeah. Yeah. Autophagy and
>> Yeah. But but also I mean there's a lot
of ways to lose weight. Um but this this
is we're talking about how to stay
sharp.
>> Keeping the flesh healthy, keeping the
plumbing open, those are arteries, you
know, vascular health. Um exercise could
do that. what we eat, giving your brain
the right materials and the mostly
plants will clear out the sludge and the
antiox, you know, the plants work
because they got they have antioxidants
and and tannins and these things that
clear the sludge that these little
molecular machines called neurons make,
right? It's that's why plants are good
for your brain. And
>> are there any that you prioritize
>> uh in plants?
>> Yes.
>> I don't I don't think it really matters.
It's hard. Again, I can't find the
experiment where they got a thousand
people eating spinach and they got a
thousand. But I can tell you over 30
years, whether it's Blue Zones or the
Mediterranean diet, now specifically
called the Mind Diet, it's Mediterranean
diet. And those people, they get a lot
less Alzheimer's than people who don't.
>> So, I I can't distill it down to that.
But Michael Poland, you know, he's
great. Mostly plants and some fish. and
then the indulgence of the burger or the
caviar or the or the vegan, you know,
burger patty. It's all it's all up to
you. But the staple is pescatarian. Then
we talked about the timing of eating,
what to eat, the timing of eating. And
then um I think the other one that's
>> just on the timing of eating thing, uh
outside of the intermittent fasting
thing, is there anything else to say on
that? It's primarily at some point a
couple of 16 hour ketones. Couple of 16
hour fasts per week is probably a good
idea.
>> Yeah. And and relatively easy to do. You
can have black coffee in the morning.
>> Um I I feel great when I do when I fast.
I I feel really really great.
>> Yeah. And and that's another another
theme I'm trying to tie in like things
that have worked for the ancients, you
know, whether it's again back to
Aristotle or fasting and different
things. Again, for people have the
luxury of this, right? Most there's a
lot of food insecurity. I'm just giving
you the conceptual answer. Um and then
the you know the the fourth thing is is
movement.
So exercise is is is movement. But uh
for my patients what we've seen is that
when you're vertical like people think
like it's got to you know you got to
have you got to have the gear. You're
out there. You're just you look like
you're auditioning for the Equinox
commercial or whatever. Like that's
great. No knocking that. But for most
people, just standing for my patients,
the trajectories of patients who can
stand and get up from a toilet and stand
and get to the couch is so much better.
Being vertical requires postural muscle
activity. So what I would say is walking
and movement
um are also cognitive uh protective. And
you mentioned exercise now. So exercise
and movement does a couple of things.
One, it keeps those arteries open that
we talked about. Uh as far as the food
well number two what to eat pescatarian
third and mind diet people can look all
these terms up. Third when to eat
intermitt and fasting for ketones and
the cognitive benefits thinking benefits
not structural.
>> Fourth is exercises that it that this
ecosystem requires
nutrients not neurotransmitters that are
being sprayed between neurons but but uh
in the millu in the garden if you will.
And there are things like growth
factors. Obviously, BDNF is a popular
one. I had a grant from the Department
of Defense studying it. I'm familiar
with it. What I want people to know is
when you exercise, it's not like it's
released from uh you know like your
thigh muscle and swims up to your brain
and says, "Hey, I'm helping you out
now." that these chemicals are housed in
the brain and exercise is the cue is the
signal for your brace brain to release
them on themselves.
>> BDNF is released from the brain for the
brain when you exercise.
>> And I think that's I think that's
powerful outside of the cardiac and
weight loss. I'm just talking about a
little bit of movement couple of times a
week and all of a sudden it starts to
feel like, hey, I can do these things.
Yeah,
>> they're pretty low bows to entry,
>> but but high high impact and proven.
>> And then the last one is you got to
think, man. You got to challenge
yourself. I mean, if you know Usain
Bolt, you you know, you ask him how to
run faster, say train, you train your
biceps. I mean, it's it's a thinking
flesh. If you don't if you don't push it
to the next level of complexity and
thought and challenge, not too hard
where you quit, just like video games.
If it's too hard to get to if to level
up, we tap out. If it's too easy, we're
not engaged. So, finding whatever you're
engaged in from puzzles to complex
conversations that it it it needs to be
challenged um with thought, with ideas,
with creativity, with reading those
novels you're reading at night.
>> So, the fresh content that's engaging
and requires you to think uh think
differently, um think wildly, think
uh in ways you haven't before. I think
that's an essential part of also that
doesn't mean everybody who who was a
professor lived longer did better than
you know people were just rocking out
not not not approaching it that way but
creative ideiation I think is as
valuable
>> as just raw processing power it's not
all about doing math and puzzles uh I
think challenging yourself to be
creative I is uh is an intelligence in
itself
>> what about the impact of stress on brain
aging
>> well I mean uh this is a this is a big
question now. So this whole thing about
cortisol is like okay
um I don't have an answer for that. I I
know people who live in a constant
stress. It seems like ba constant stress
is bad for you in a lot of ways. I also
know thrill seekers uh surgeons athletes
every time they do something exciting
cortisol is up. Okay. um and they don't
have accelerated brain in you know brain
aging. So I don't have an answer for
whether cortisol is doing it, whether
stress is doing it, whether it's just a
rough life, whether it's uh struggling
with thoughts you can't control which
revert back to your brain and injure
your brain. I don't have an answer for
that. But I think what the story I would
tell you about that is there's a tumor
called fio chromosytoma and it sits on
top of the kidneys and it releases all
this all these what basically look like
you're extremely stressed out. Um
>> and is that how it feels as well? That's
the essential question, my man. They
they don't come in like ah
that is the essential question, my man.
That's a banger. That's to So I don't
have the answer, but I'm leaving you
with things. I hope I want to know the
answer, but the brain contextualizes all
of this surge of stuff that's happening.
>> Interesting. I I do you know Rick
Hansen? You familiar with Rick? Neuro
neuro uh science guy. He wrote
hardwiring happiness.
>> I read that and spoke to him. He became
a good friend. And then the more
neuroscientists that I speak to, the
more I realize that a lot of the stories
that we tell ourselves are kind of
repurposing mechanistically what's
happening in the mind. But the weird
thing is
>> nobody talks about the story you tell
yourself about your knee injury,
>> right? You know, someone someone snapped
their ACL and it's not about thinking
your ACL back into contact. We
understand that there's a mechanism
that's going on in here and that that
really needs to be fixed and that
there's a pretty wellestablished process
that you go through in terms of rehab
and it's progressive overload and
tendons really love to be under time and
detention. So, you're going to do this
and you're going to get range back and
there's a combination of stretching that
you get with strength and the more range
that you get the less you know all of
this. It's mechanistically very well
understood. But the thing is there is no
massively phenomenological sense of
having an ACL.
There is one for everything that happens
in the brain. And I really got into
psychology, human nature, you know,
Angela Duckworth or James Clears of the
world,
>> Morgan Hels, you know, a lot of people
that write very astutely about human
nature and about psychology and I go
into evolutionary psychology, which is
even maybe one step further removed,
right? That's like the source code and
that a lot of accusations of just those
stories and things like that
and that's really cool and compelling.
The more that I spend time thinking
about this stuff, the more I try and
come back to mechanistically what's
happening in the brain because it really
does feel like for instance with
gratitude from Rick's uh uh uh
understanding here, he basically sees
happiness as your ease of access to uh
being grateful about what's going on.
And he has a very simple process that is
well understood and just reflects the
mechanism of what goes on in the brain
of have an experience, enrich it and
absorb it. And it's just this little
acronym that you go through. I thought
that's so great. That feels to me one of
the problems that a lot of people have
when they read stuff to do with human
nature and psychology is it feels so
[ __ ] wishy-washy. You're like I I
give me something to grab onto. It's
like my puppy's example. But let me just
jump in right there. Um,
I like that. And what really just gets
me jacked in a positive way is when I
see that our behavior and our minds work
in a way that's actually reflected at
the neuronal level.
>> Mhm. You know, so like if you stress
stem cell reservoirs just enough,
they'll make one of themselves and
release a new neuron. So they're always
replenishing them. They never they're
inexhaustible in that way, right?
They're stem cells.
>> But if you stress them out too much,
they'll go into scinessence or they'll
die.
>> And then you start to realize, wait,
that's kind of how life is, right? And
then you then I like to take it all the
way to like International Space Station.
and there's not enough gravity. Those
bone cells
uh in space in our thigh bone when they
come back on on the ground, they got to
rehab for a week or two. The lack of
gravitational stress leads to withering
of osteoccytes for astronauts. And so
the same concepts in bone cells in space
or stress in the human brain that there
is a necessary amount of stress that
leads to growth but
>> if it's too much we fracture y
>> if it's not enough we don't blossom and
I and I and I like to take those
concepts to then coping and so for
example like this thing about resilience
was tripping me up for a little while
like what does that mean you know like
be resilient like I I always try to
think like I got to be able to say this
to my sons. I got to be able to say to a
newly diagnosed brain cancer patient. Y
>> and and what I learned from that is um
it's sort of their systemic and
processive uh resilience which is
basically like the resilience you bring
to the fight, you know, the the strength
you bring to the fight and then the
process what the fight reveals in you.
And and what I like about that is that
each cell, each person, each human is in
their own individual path
>> and has accumulated a set of
experiences. And my hope is universal
coping skills and they're ready to
engage the world in front of them. And
that could be a lottery, that could be
falling in love, that could be being
diagnosed with cancer. and they're
coming equipped with some skills uh and
in that cyclical nature of stress and
growth that happens repeatedly in our
bodies like that's actually what's
happening in our lives. There's a cycl
cyclical nature of a springtime in our
cells and our body, a winter in our
cells and our body and life and that
there is no like linear trajectory
towards wellness or a moment of arrival
or of of final clarity cuz you just
don't know what the challenge or the
gift in front of you is. Well, certainly
one thing that I can say with almost
absolute certainty is that you do not
develop capacity to deal with things
while you're dealing with things.
>> Your capacity to deal with things is
almost always developed in advance and
revealed during. So, uh this one of the
best justifications for mindfulness that
mindfulness is preparing for the worst
day of your life. That's what meditation
is. Meditation is preparing for the
worst day of your life. If it's the day
that you lose your job and your dad
passes away on the same morning, it's
the day that your partner gets a cancer
diagnosis and you find out that you're
no longer employed or whatever it might
be.
If you're in the thick of it right now,
I've been in the thick of it for a good
bit of the last 18 months.
You're doing your very best to not go
under. Yeah.
>> And then you're fight.
And then when you get a break and it's
really actually this is interesting.
It's only difficult times that reveal to
you, holy [ __ ] I couldn't really make
much progress during that. I was just
trying to survive. The urgent outweighed
the important so much that all I could
do was kind of try and hold it together.
Okay. So, what's the implication of
that? When you do not have something
that's super urgent in front of you,
when you're not putting out fires, it's
a really, really, really good time to
develop some more capacity.
>> Psychological resolve.
>> Yes. That's the time that you try to get
your meditation habit in. That's the
time that you work on your health. You
refine you're training for the fight
that has yet to come with a toolkit that
I'm I'll never finally make, but I I
mean, that's what I'm trying to get at.
And back to the cells. Cells go through
a period of dormcancy.
>> Mh. And at that point,
not dying is is actually the victory.
And then there's a springtime just like
in nature and this happens in our
biology. And I think it happens in our
psychology that you're talking about.
And that those moments there's a
temporal nature. Uh there's like
reflection and going back and saying,
"Okay, what are the lessons I learned?
How would I handle it better forward?" I
I love all that. I'm actually trying to
come up with when you feel like you're
dry drowning or about to fall apart in
that short temporal window. Are are
there things we can do at that time? Um
how do we interject right then?
>> Yeah, the time-sensitive maneuvers.
>> Yeah, I like
>> I very much like being able to step in
on stuff that's acute. It's all well and
good talking about building up your
resilience and all the rest of it, but
if you're in the [ __ ] fight, you go,
"Hey, I can't go back six months ago and
start a meditation practice. Tell me
what to do right now." Right. And so
what I would say is if uh you know the I
would say is that uh
urges that hijack the body are very
fascinating to me. um when though when
the thought is now recruits the body
there's a whole new fight whether that's
addiction whether that's desire
>> because now there's a feeling that if I
don't go in this harmful direction
uh that I will feel ill so now you're
not just trying to stop a thought let's
take the example of having a cigarette
again it's not just oh don't have a
cigarette don't have a cigarette it
could cause cancer down the road it's
bad it's bad you promised everybody you
wouldn't they might smell it on you
whatever thinking, don't look at it.
Look at those shiny boxes of the gas
station, right? But then when you have
that waft and it goes from the nerves in
your old factory bulb to to your frontal
lobe and now you're just like, "Oh man,
that's reminds you of so much." People
will have physiologic changes. So now
the fight is controlling your mind and
body and I believe the maneuvers are
different when it goes from your mind to
your body and the management of bodily
urges um is uh requires bodily
techniques. Uh breathing techniques are
uh the same ones I use in surgery.
Sometimes when I was learning and you
feel like that around that corner that
tumor is going to run away from you. I
mean, you gota you you gotta not you
gotta it's gonna either you're going to
freak out or you're not going to freak
out. And the simplest thing I can tell
you is like when you hyperventilate it
creates a feeling of anxiety. Well, you
got to take it the other other way. The
first maneuver is just control your
breathing. Nobody knows. The room is
just like d and you're just like whoa
whoa whoa whoa whoa. You know this could
this could run away from me. And so I
have my own maneuver that I do in that
moment is just stop talking, you know,
uh or and there's something I call out.
I say, "I need 15." And they're like,
"Okay, everybody pay attention back to
back to your positions that he might
say, I need this from the wall. I need
this from the wall."
And the whole thing is just just get
that get that breathing paced. I'm not
talking about one nostril. I'm not
getting into all that. I'm just trying
to tell you physiologically if I pace my
breathing I can slow down this swell of
fear and panic that's in my guts when
things run away from me. I try to use
the same thing with with a lover and
with a conflict, but that's a specific
toolkit that has a physiologic basis
that I can explain that the ancients use
is is in the acute moment. And I'm
hunting now, you know, the next year or
so. But are there other maneuvers that
uh
>> that we're all equipped with that can
work while you're um you know, while you
feel like uh you're falling apart or
you're drowning or you're struggling,
you know, at that moment. Not in
Riverview. Not in the future. I will.
>> Right now.
>> Right now, what do I do?
>> Is there anything you've ever seen in
surgery that shook your belief in
science?
>> Um,
not in surgery.
Um, surgery is a physical performance is
ballet.
But um
I have had um
I have had patients in the psychological
sciences. I've had patients where I just
look I'm like I don't know the the I
don't know how the great majority of
cancer patients get dressed come in and
are ready to get the worst news of their
lives every 3 months when we do the
scans. It's come back or didn't go away.
I mean, it's just it's just so heavy and
the
the what the fight brings out in them or
the coping skills they've brought and
it's inconsistent. I'll get to the the
more philosophical question. It's
inconsistent. Somebody comes in, they've
got the wellness techniques, they're the
CEO, they get hit with that C-word. It's
you don't know what you're going to get.
And then somebody comes in, they're
struggling with something, they look
disheveled. You're like, "This person's
not going to handle this well." it
brings out something in them. So I think
this feeling that that arrival in some
sort of wellness and achievement or
clarity understanding of life is
misguided because we don't know what's
coming next. I think it's cyclical.
Develop your skills time-sensitive
skills in the review being prepared for
being what what's forward. Uh that's the
way I've been approaching it. And as far
as shook my belief in science, uh I
would say something recently has uh uh
liberated my view in science that it
it's through science we can have
understanding that we might not. So
there are these near-death experiences.
Those electrodes are being recorded.
People in uh Canada and studies starting
to come out that when the heart stops
for the first few minutes afterwards,
the brain just deploys all its chemicals
and electricity. So whereas other organs
whimper to death like the brain is
struggling the heart stops and then if
you measure the electricity because you
can actually have a DNR you can say look
if I have a heart attack don't touch me
do not resuscitate and they're still
monitoring you still get a live feed of
the brain electricity. So you would
think the heart stops and the brain
electricity stops but it goes for a
minute or two afterwards and it's wild.
>> It's fierce. It's not like Yeah. It's a
So that's a measurement. What does it
mean? That's for everybody to explo
explore. But to me, that's like, okay,
so there's there'll always be just
amazing neuroscience information coming
from hospitals and patients. That's a
little bit more than just scanners,
>> right? And when those people are
resuscitated,
and why do they all universally say, I
saw it's a film strip of my old life.
And you know there's a consistent
pattern of what happens if you drown or
if you have a near-death experience and
are resuscitated in whichever manner
they come back reporting the same thing
film strip of their life wide stories
they saw loved ones. And when you look
at the electricity it's very consistent
with dreaming and memories. So to me I
love the fact that now we might be able
to explain why near-death experiences
are a consistent perception or or
experience for for people. So, I love
seeing that stuff come out.
>> Yeah. I'm interested in what
working with terminal patients has
taught you about living life. Well,
>> everything. Um,
yeah. Everything. Um,
you know, it's has thousands now. I
mean,
uh, I'm 52.
Massive experience. I've got three adult
sons. massive life experience. But since
25, I've been taking care of some of the
sickest people in the hospital. Brain
injury for 10 years.
>> Half your life.
>> Yeah. I was a kid when I started, you
know. I mean, I look at I look at people
in their 20s. I'm like, woo. Um I was
like 26 or 27. I wrote about it for a
Vice article. I withdrew care. I mean, I
help families land their patients, I
mean, their family members and remove
the breathing tubes and say their last
rights and wishes and all the different
cultural elements that come into it in
ICUs. I was 27 years old and I started
to see uh there were patterns
um in the ways uh the brain and mind
respond when the finish line comes
closer. It's not trauma. You're you're
gone. You don't know it. It's okay.
Three years, two to five, seven, you
can't quantify it, but you know it's
coming now. It's in it's in sight. And
um
they had a universal
all of them say the same thing again
when that finish line comes into view.
And it's the lessons I think everybody
else talks about, but they have a
similar thing about reconciliation,
forgiveness,
about having spent more time with their
children. Usually it was like busy busy
dads at that time, my 20s, you know, and
I and I incorporate that. I had a lab. I
raised my kids. Didn't take them just to
the baseball games, but the practices
spent a lot of time to them. And that
they seemed unencumbered. they weren't
so
the little things don't get to them as
much. And the question then becomes how
do we take those lessons without
actually having you know if
hypothetically the finish god willing is
25 years away from me how can I actually
live it like it's 5 years from now and
that's the lesson that my cancer
patients have taught me is one um start
now with what you would if you had you
know that you do a 5year curves and two
uh build your coping skills uh because
the ones that I saw do Well,
uh, they had techniques just I'm just
coming coming back to this and like I
learned one from one like every 3 months
the scans let's just imagine brain scan
2 three hours 6 hours who knows what
it's going to you show up in clinic it's
another hour to wait to hear it for
somebody and they so they would do this
thing where like look the 11 weeks in
between
um I can I can hold on to myself and say
this is not the time to be stress
stressed, but I need to have a week when
I'm just completely losing it.
>> Like, you can't just not be stressed
about that. But they were able to
compartmentalize it to have like 11 good
weeks and then another shitty week
because, oh my god, I got another get a
brain scan and see Dr. John De. And so I
started to see those techniques they
were using uh to make the most of their
cancer journey. Support network is nice,
but uh the support network can be
surprising. It's not always who you
think it is. you know, once that cancer
word arrives,
>> relationships break up, surprising
relationships form.
>> And so, um, you know, no triumph is
forever and no tragedy is forever. But
>> if you come equipped with your own
personal and psychological toolkit,
um, you know, we make the most of this
run.
>> Heck yeah. Dr. John, ladies and
gentlemen, where should people go? You
want to keep up to date with everything
you've got going on?
>> Just uh, I don't know. Just just, uh,
you know, I'm I'm a surgeon at City of
Oak Cancer Center. I think that's the
easiest thing is look up Dr. John Dell
at City of Hope and then you know things
will pop up. But appreciate you having
me on.
>> I appreciate you too, man.
>> Thank you very much for tuning in. If
you enjoyed that episode, you will love
this one with Mr. Naval Ravakan. It's
first episode in six years. Come on,
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